Publications
An initial blueprint for myogenic differentiation.. Genes Dev. 19(5):553-69.
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2005. Retinoblastoma tumor suppressor protein-dependent methylation of histone H3 lysine 27 is associated with irreversible cell cycle exit.. J Cell Biol. 179(7):1399-412.
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2007. XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks.. Mol Cell. 27(1):53-66.
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2007. E2f3b plays an essential role in myogenic differentiation through isoform-specific gene regulation.. Genes Dev. 23(1):37-53.
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2009. Traf7, a MyoD1 transcriptional target, regulates nuclear factor-κB activity during myogenesis.. EMBO Rep. 11(12):969-76.
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2010. A CHOP-regulated microRNA controls rhodopsin expression.. J Cell Biol. 192(6):919-27.
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2013.
Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis.. Science. 345(6192):98-101.
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2014. A conformational RNA zipper promotes intron ejection during non-conventional XBP1 mRNA splicing.. EMBO Rep. 16(12):1688-98.
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2015. Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits.. Elife. 4:e08153.
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2015. Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer.. Mol Cancer Ther. 14(3):642-8.
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2016.
Targeting IRE1 with small molecules counteracts progression of atherosclerosis.. Proc Natl Acad Sci U S A.
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2018.
Disruption of IRE1α through its kinase domain attenuates multiple myeloma.. Proc Natl Acad Sci U S A.
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2019. In vitro RNA Cleavage Assays to Characterize IRE1-dependent RNA Decay. Bio-protocol. 9(14)
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2020.
A Fast and Accessible Method for the Isolation of RNA, DNA, and Protein to Facilitate the Detection of SARS-CoV-2.. J Clin Microbiol.
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2020. Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response.. Nat Commun. 11(1):2401.
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2020. The impact of SARS-CoV-2 in dementia across Latin America: A call for an urgent regional plan and coordinated response.. Alzheimers Dement (N Y). 6(1):e12092.
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2020.