Publications

Found 11 results
Author Title [ Type(Desc)] Year
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Journal Article
Sherbenou DW, Aftab BT, Su Y, Behrens CR, Wiita A, Logan AC, Acosta-Alvear D, Hann BC, Walter P, Shuman MA et al..  2016.  Antibody-drug conjugate targeting CD46 eliminates multiple myeloma cells.. J Clin Invest.
Harnoss JM, Le Thomas A, Shemorry A, Marsters SA, Lawrence DA, Lu M, Chen Y-CAriel, Qing J, Totpal K, Kan D et al..  2019.  Disruption of IRE1α through its kinase domain attenuates multiple myeloma.. Proc Natl Acad Sci U S A.
Harnoss JM, Le Thomas A, Shemorry A, Marsters SA, Lawrence DA, Lu M, Chen Y-CAriel, Qing J, Totpal K, Kan D et al..  2019.  Disruption of IRE1α through its kinase domain attenuates multiple myeloma.. Proc Natl Acad Sci U S A.
Harnoss JM, Le Thomas A, Shemorry A, Marsters SA, Lawrence DA, Lu M, Chen Y-CAriel, Qing J, Totpal K, Kan D et al..  2019.  Disruption of IRE1α through its kinase domain attenuates multiple myeloma.. Proc Natl Acad Sci U S A.
Dufey E, San Pedro JManuel Bra, Eggers C, González-Quiroz M, Urra H, Sagredo AI, Sepulveda D, Pihán P, Carreras-Sureda A, Hazari Y et al..  2020.  Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response.. Nat Commun. 11(1):2401.
Dufey E, San Pedro JManuel Bra, Eggers C, González-Quiroz M, Urra H, Sagredo AI, Sepulveda D, Pihán P, Carreras-Sureda A, Hazari Y et al..  2020.  Genotoxic stress triggers the activation of IRE1α-dependent RNA decay to modulate the DNA damage response.. Nat Commun. 11(1):2401.
Acosta-Alvear D, Cho MY, Wild T, Buchholz TJ, Lerner AG, Simakova O, Hahn J, Korde N, Landgren O, Maric I et al..  2015.  Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits.. Elife. 4:e08153.
Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn BR, Li H, Gamache K, Gallagher CM, Ang KK-H, Wilson C et al..  2013.  Pharmacological brake-release of mRNA translation enhances cognitive memory.. Elife. 2:e00498.
Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn BR, Li H, Gamache K, Gallagher CM, Ang KK-H, Wilson C et al..  2013.  Pharmacological brake-release of mRNA translation enhances cognitive memory.. Elife. 2:e00498.
Tufanli O, Akillilar PTelkoparan, Acosta-Alvear D, Kocaturk B, Onat UInci, Hamid SMuhammad, Çimen I, Walter P, Weber C, Erbay E.  2017.  Targeting IRE1 with small molecules counteracts progression of atherosclerosis.. Proc Natl Acad Sci U S A.
Li X, Colvin T, Rauch JN, Acosta-Alvear D, Kampmann M, Dunyak B, Hann B, Aftab BT, Murnane M, Cho M et al..  2015.  Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer.. Mol Cancer Ther. 14(3):642-8.