Sperm-binding proteins.

TitleSperm-binding proteins.
Publication TypeJournal Article
Year of Publication1995
AuthorsFoltz KR
JournalInt Rev Cytol
Date Published1995
KeywordsAnimals, Egg Proteins, Female, Male, Membrane Glycoproteins, Mice, Receptors, Cell Surface, Sperm-Ovum Interactions, Spermatozoa

Gamete recognition and binding are mediated by specific proteins on the surface of the sperm and egg. Identification and characterization of some of these proteins from several model systems, particularly mouse and sea urchin, have focused interest on the general properties and functions of gamete recognition proteins. Sperm-binding proteins located in egg extracellular coats as well as sperm-binding proteins that are localized to the egg plasma membrane are presented in the context of their structure and function in gamete binding. Unifying and disparate characteristics are discussed in light of the diverse biology of fertilization among species. Outstanding questions, alternative mechanisms and models, and strategies for future work are presented.

Alternate JournalInt. Rev. Cytol.
PubMed ID8522421
Grant ListR01 HD30698 / HD / NICHD NIH HHS / United States