The molecular basis of sea urchin gamete interactions at the egg plasma membrane.

TitleThe molecular basis of sea urchin gamete interactions at the egg plasma membrane.
Publication TypeJournal Article
Year of Publication1993
AuthorsFoltz KR, Lennarz WJ
JournalDev Biol
Volume158
Issue1
Pagination46-61
Date Published1993 Jul
ISSN0012-1606
KeywordsAmino Acid Sequence, Animals, Cell Membrane, Female, Glycoproteins, Heat-Shock Proteins, Male, Molecular Sequence Data, Receptors, Cell Surface, Sea Urchins, Sequence Homology, Amino Acid, Sperm-Ovum Interactions, Spermatozoa
Abstract

Fertilization is the result of a series of well-choreographed interactions between molecules located on the surfaces of the egg and the sperm. The recent molecular characterizations of several of these surface molecules has led to a greater understanding of their roles in gamete recognition and binding. We present a review of these recent advances with emphasis on the sea urchin, a classic system for the study of fertilization. In particular, the structure and function of the sea urchin egg plasma membrane receptor for sperm, a novel cell recognition molecule, is discussed.

DOI10.1006/dbio.1993.1167
Alternate JournalDev. Biol.
PubMed ID8392471
Grant ListHD18590 / HD / NICHD NIH HHS / United States