Research

calcium tapestry threads

How does sperm-egg interaction result in the activation of the egg? In all animals, an increase of cytosolic calcium levels is essential, but how is this regulated and what are the down stream targets? Our lab tries to unravel and understand the threads of the "calcium tapestry" in the egg. Click on the title for more information!

simple model

What is the molecular basis of gamete binding and fusion at the egg plasma membrane? Is fertilization in free  spawning organisms akin to self/non-self recognition? Click on the title for more information!