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A Biophysical ‘Smoking Gun’ Scientists studying Alzheimer’s disease begin to unravel how the protein tau transitions from soluble liquid to solid fibrous tangle

July 12, 2017

While much about Alzheimer’s disease remains a mystery, scientists do know that part of the disease’s progression involves a normal protein called tau, aggregating to form ropelike inclusions within brain cells that eventually strangle the neurons. Yet how this protein transitions from its soluble liquid state to solid fibers has remained unknown — until now.

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