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Tracking Down Mutations Cell by Cell.

TitleTracking Down Mutations Cell by Cell.
Publication TypeJournal Article
Year of Publication2016
AuthorsKosik KS
JournalNeuron
Volume89
Issue6
Pagination1126-7
Date Published2016 Mar 16
ISSN1097-4199
Abstract

Using somatic cell nuclear transfer, Hazen et al. (2016) examined clonally expanded single neurons for mutations and found ∼100 mutations from a variety of classes. Post-mitotic mutations in individual neurons represent an exploratory direction for finding fundamental origins of neurodegeneration.

DOI10.1016/j.neuron.2016.02.042
Alternate JournalNeuron
PubMed ID26985720