Athinarayanan SJ, Roberts CGP, Vangala C, Shetty GK, McKenzie AL, Weimbs T, Volek JS. The case for a ketogenic diet in the management of kidney disease. BMJ Open Diabetes Res Care. 2024 ;12(2):e004101.
Torres JA, Holznecht N, Asplund DA, Amarlkhagva T, Kroes B, Rebello J, Agrawal S, Weimbs T. A Combination of ß-Hydroxybutyrate and Citrate Ameliorates Disease Progression in a Rat Model of Polycystic Kidney Disease. Am J Physiol Renal Physiol. 2024 ;326:F352-F368.
Weimbs T, Saville J, Kalantar-Zadeh K. Ketogenic Metabolic Therapy for Chronic Kidney Disease. Clinical Kidney Journal. 2024 ;17:sfad273.


Cukoski S, Lindemann CHeinrich, Arjune S, Todorova P, Brecht T, Kühn A, Oehm S, Strubl S, Becker I, Kämmerer U, Torres JAlexander, Meyer F, Schömig T, Hokamp NGroße, Siedek F, Gottschalk I, Benzing T, Schmidt J, Antczak P, Weimbs T, Grundmann F, Müller R-U. Feasibility and impact of ketogenic dietary interventions in polycystic kidney disease: KETO-ADPKD-a randomized controlled trial. Cell Rep Med. 2023 ;4:101283.
Pellegrini H, Sharpe EH, Liu G, Nishiuchi E, Doerr N, Kipp KR, Chin T, Schimmel MF, Weimbs T. Cleavage fragments of the C-terminal tail of polycystin-1 are regulated by oxidative stress and induce mitochondrial dysfunction. J Biol Chem. 2023 ;299:105158.


Oehm S, Steinke K, Schmidt J, Arjune S, Todorova P, Lindemann C, Wöstmann F, Meyer F, Siedek F, Weimbs T, Müller R-U, Grundmann F. RESET-PKD: A pilot trial on short-term ketogenic interventions in autosomal dominant polycystic kidney disease. Nephrol Dial Transplant. 2022 .
Akbari M, West JD, Doerr N, Kipp KR, Marhamati N, Vuong S, Wang Y, Rinschen MM, Talbot JJ, Wessely O, Weimbs T. Restoration of atypical protein kinase C ζ function in autosomal dominant polycystic kidney disease ameliorates disease progression. Proc Natl Acad Sci U S A. 2022 ;119(30):e2121267119.
Tonum K, Srimai N, Chabang N, Fongsupa S, Tuchinda P, Torres JA, Weimbs T, Soodvilai S. Pharmacological Effects of Panduratin A on Renal Cyst Development in In Vitro and In Vivo Models of Polycystic Kidney Disease. International Journal of Molecular Sciences. 2022 ;23:4328-4343.


Strubl S, Oehm S, Torres JA, Grundmann F, Haratani J, Decker M, Vuong S, Bhandal AK, Methot N, Haynie-Cion R, Meyer F, Siedek F, Korst U, Müller RU, Weimbs T. Ketogenic Dietary Interventions in Autosomal-Dominant Polycystic Kidney Disease (ADPKD)– A Retrospective Case Series Study: First insights into Feasibility, Safety and Effects. Clinical Kidney Journal. 2021 ;15:1079-1092.


Dafinger C, Mandel AM, Braun A, Göbel H, Burgmaier K, Massella L, Mastrangelo A, Dötsch J, Benzing T, Weimbs T, Schermer B, Liebau MC. The carboxy-terminus of the human ARPKD protein fibrocystin can control STAT3 signalling by regulating SRC-activation. J Cell Mol Med. 2020 ;24:14633–14638.
Giovannone AJ, Reales E, Bhattaram P, Nackeeran S, Monahan AB, Syed R, Weimbs T. The Habc domain of syntaxin 3 is a ubiquitin binding domain. Sci Rep. 2020 ;10(1):21350.
Strubl S, Torres JA, Spindt AK, Pellegrini H, Liebau MC, Weimbs T. STAT signaling in polycystic kidney disease. Cellular Signalling. 2020 ;72:109639.
Cho Y, Tong A, Craig JC, Mustafa RA, Chapman A, Perrone RD, Ahn C, Fowler K, Torres V, Gansevoort RT, Ong ACM, Coolican H, Kao JTze-Wah, Harris T, Gutman T, Shen JI, Viecelli AK, Johnson DW, Au E, El-Damanawi R, Logeman C, Ju A, Manera KE, Chonchol M, Odland D, Baron D, Pei Y, Sautenet B, Rastogi A, Sharma A, et al. Establishing a Core Outcome Set for Autosomal Dominant Polycystic Kidney Disease: Report of the Standardized Outcomes in Nephrology-Polycystic Kidney Disease (SONG-PKD) Consensus Workshop. Am J Kidney Dis. 2020 ;77:255-263.


Billot K, Coquil C, Villiers B, Josselin-Foll B, Desban N, Delehouze C, Oumata N, Le Meur Y, Boletta A, Weimbs T, Grosch M, Witzgall R, Saunier S, Fischer E, Pontoglio M, Fautrel A, Mrug M, Wallace DPaul, Tran PV, Trudel M, Bukanov NO, Ibraghimov-Beskrovnaya O, Meijer L. Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8. Am J Physiol Renal Physiol. 2018 ;315:F57–F73.
Giovannone AJ, Winterstein C, Bhattaram P, Reales E, Low SH, Baggs JE, Xu M, Lalli MA, Hogenesch JB, Weimbs T. Soluble syntaxin 3 functions as a transcriptional regulator. J Biol Chem. 2018 ;293:5478-5491.
Giovannone AJ, Reales E, Bhattaram P, Fraile-Ramos A, Weimbs T. Tracking Endocytosis and Intracellular Trafficking of Epitope-tagged Syntaxin 3 by Antibody Feeding in Live, Polarized MDCK Cells. Bio-Protocol. 2018 ;8(3):e2453.
Weimbs T, Shillingford JM, Torres J, Kruger SL, Bourgeois BC. Emerging targeted strategies for the treatment of autosomal dominant polycystic kidney disease. Clinical Kidney Journal. 2018 ;11(suppl_1):i27–i38.


Doerr N, Wang Y, Kipp KR, Liu G, Benza JJ, Pletnev V, Pavlov TS, Staruschenko A, Mohieldin AM, Takahashi M, Nauli SM, Weimbs T. Regulation of Polycystin-1 Function by Calmodulin Binding. PLoS One. 2016 ;11(8):e0161525.
Soo-Hoo L, Banna CD, Radeke CM, Sharma N, Albertolle ME, Low SH, Weimbs T, Vandenberg CA. The SNARE Protein Syntaxin 3 Confers Specificity for Polarized Axonal Trafficking in Neurons. PLoS One. 2016 ;11(9):e0163671.


Rothé B, Leal-Esteban L, Bernet F, Urfer S, Doerr N, Weimbs T, Iwaszkiewicz J, Constam DB. Bicc1 polymerization regulates the localization and silencing of bound mRNA. Mol Cell Biol. 2015 ;35:3339-3353.


Talbot JJ, Song X, Wang X, Rinschen MM, Doerr N, LaRiviere WB, Schermer B, Pei YP, Torres VE, Weimbs T. The cleaved cytoplasmic tail of polycystin-1 regulates Src-dependent STAT3 activation. J Am Soc Nephrol. 2014 ;25(8):1737-48.


Weimbs T, Talbot JJ. STAT3 signaling in polycystic kidney disease. Drug Discovery Today: Disease Mechanisms. 2013 ;10(3-4):e113-e118.


Shillingford JM, Piontek KB, Germino GG, Weimbs T. Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1. Journal of the American Society of Nephrology. 2010 ;21:489–497.
Torres VE, Boletta A, Chapman A, Gattone V, Pei Y, Qian Q, Wallace DP, Weimbs T, Wüthrich RP. Prospects for mTOR inhibitor use in patients with polycystic kidney disease and hamartomatous diseases. Clinical Journal of the American Society of Nephrology. 2010 ;5:1312–1329.


Mistry AC, Mallick R, Klein JD, Weimbs T, Sands JM, Fröhlich O. Syntaxin specificity of aquaporins in the inner medullary collecting duct. American Journal of Physiology-Renal Physiology. 2009 ;297:F292–F300.


Kidd GJ, Yadav VK, Huang P, Brand SL, Low SH, Weimbs T, Trapp BD. A dual tyrosine-leucine motif mediates myelin protein P0 targeting in MDCK cells. Glia. 2006 ;54:135–145.
Sharma N, Low SH, Misra S, Pallavi B, Weimbs T. Apical targeting of syntaxin 3 is essential for epithelial cell polarity. The Journal of Cell Biology. 2006 ;173:937–948.


Fei B, Flask C, Wang H, Pi A, Wilson DL, Shillingford J, Murcia N, Weimbs T, Duerk JL. Image segmentation, registration and visualization of serial MR images for therapeutic assessment of polycystic kidney disease in transgenic mice. Conf Proc IEEE Eng Med Biol Soc. . 2005 :467–469.


Fan S, Hurd TW, Liu C-J, Straight SW, Weimbs T, Hurd EA, Domino SE, Margolis B. Polarity proteins control ciliogenesis via kinesin motor interactions. Current Biology. 2004 ;14:1451–1461.
Tartakoff AM, A Matera G, Pimplikar SW, Weimbs T. Regulation of nuclear functions–nucleocytoplasmic transport in context. European Journal of Cell Biology. 2004 ;83:185–192.


Weimbs T, Low SH, Li X, Kreitzer G. SNAREs and epithelial cells. Methods. 2003 ;30:191–197.
Kreitzer G, Schmoranzer J, Low SH, Li X, Gan Y, Weimbs T, Simon SM, Rodriguez-Boulan E. Three-dimensional analysis of post-Golgi carrier exocytosis in epithelial cells. Nature Cell Biology. 2003 ;5:126–136.


Li X, Low SH, Miura M, Weimbs T. SNARE expression and localization in renal epithelial cells suggest mechanism for variability of trafficking phenotypes. American Journal of Physiology-Renal Physiology. 2002 ;283:F1111–F1122.
van Ijzendoorn SCD, Tuvim MJ, Weimbs T, Dickey BF, Mostov KE. Direct interaction between Rab3b and the polymeric immunoglobulin receptor controls ligand-stimulated transcytosis in epithelial cells. Developmental Cell. 2002 ;2:219–228.
Low SH, Marmorstein LY, Miura M, Li X, Kudo N, Marmorstein AD, Weimbs T. Retinal pigment epithelial cells exhibit unique expression and localization of plasma membrane syntaxins which may contribute to their trafficking phenotype. Journal of Cell Science. 2002 ;115:4545–4553.


Lim S-N, Bonzelius F, Low SH, Wille H, Weimbs T, Herman GA. Identification of discrete classes of endosome-derived small vesicles as a major cellular pool for recycling membrane proteins. Molecular Biology of the Cell. 2001 ;12:981–995.


Low SH, Miura M, Roche PA, Valdez AC, Mostov KE, Weimbs T. Intracellular redirection of plasma membrane trafficking after loss of epithelial cell polarity. Molecular Biology of the Cell. 2000 ;11:3045–3060.


Low SH, Roche PA, Anderson HA, van Ijzendoorn SCD, Zhang M, Mostov KE, Weimbs T. Targeting of SNAP-23 and SNAP-25 in polarized epithelial cells. Journal of Biological Chemistry. 1998 ;273:3422–3430.
Low SH, Chapin SJ, Wimmer C, Whiteheart SW, Kömüves LG, Mostov KE, Weimbs T. The SNARE machinery is involved in apical plasma membrane trafficking in MDCK cells. The Journal of Cell Biology. 1998 ;141:1503–1513.


Weimbs T, Low SH, Chapin SJ, Mostov KE, Bucher P, Hofmann K. A conserved domain is present in different families of vesicular fusion proteins: a new superfamily. Proceedings of the National Academy of Sciences. 1997 ;94:3046–3051.


Low SH, Chapin SJ, Weimbs T, Kömüves LG, Bennett MK, Mostov KE. Differential localization of syntaxin isoforms in polarized Madin-Darby canine kidney cells. Molecular Biology of the Cell. 1996 ;7:2007-2018.


Mostov KE, Altschuler Y, Chapin SJ, Enrich C, Low SH, Luton F, Richman-Eisenstat J, Singer KL, Tang K, Weimbs T. Regulation of protein traffic in polarized epithelial cells: the polymeric immunoglobulin receptor model. Cold Spring Harbor Symposia on Quantitative Biology. 1995 ;60:775–781.


Weimbs T, DICK T, Stoffel W, BOLTSHAUSER E. A point mutation at the X-chromosomal proteolipid protein locus in Pelizaeus-Merzbacher disease leads to disruption of myelinogenesis. Biological Chemistry Hoppe-Seyler. 1990 ;371:1175–1184.