Among the most devastating infectious diseases worldwide are insect-borne diseases that are spread by mosquitoes. One such mosquito vector, Aedes aeypti, is of particular concern because it spreads the viruses that cause diseases such as Dengue and Zika, which are increasing in incidence. Using molecular genetic approaches, our laboratory is developing transgenic forms of Aedes aeypti that are intended to suppress this insect vector. We are also identifying the receptors and channels that Aedes aegypti uses to find people.