Title | Mg2+ homeostasis: the Mg2+nificent TRPM chanzymes |
Publication Type | Journal Article |
Year of Publication | 2003 |
Authors | Montell C |
Journal | Curr Biol |
Volume | 13 |
Pagination | R799-801 |
Date Published | 2003 Oct 14 |
ISSN | 0960-9822 |
Keywords | Homeostasis, Humans, Ion Channels, Magnesium, Protein Conformation, Protein Kinases, TRPM Cation Channels |
Abstract | TRPM6 and TRPM7 are distinct from all other ion channels in that they are composed of linked channel and protein kinase domains. Recent studies demonstrate that these 'chanzymes' are essential for Mg(2+) homeostasis, which is critical for human health and cell viability. |
Alternate Journal | Curr. Biol. |
PubMed ID | 14561419 |