Mg2+ homeostasis: the Mg2+nificent TRPM chanzymes

TitleMg2+ homeostasis: the Mg2+nificent TRPM chanzymes
Publication TypeJournal Article
Year of Publication2003
AuthorsMontell C
JournalCurr Biol
Volume13
PaginationR799-801
Date Published2003 Oct 14
ISSN0960-9822
KeywordsHomeostasis, Humans, Ion Channels, Magnesium, Protein Conformation, Protein Kinases, TRPM Cation Channels
Abstract

TRPM6 and TRPM7 are distinct from all other ion channels in that they are composed of linked channel and protein kinase domains. Recent studies demonstrate that these 'chanzymes' are essential for Mg(2+) homeostasis, which is critical for human health and cell viability.

Alternate JournalCurr. Biol.
PubMed ID14561419