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Diego Acosta-Alvear Lab | Molecular, Cellular, and Developmental Biology | UC Santa Barbara

Diego Acosta-Alvear Lab | Molecular, Cellular, and Developmental Biology | UC Santa Barbara

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Welcome to the Acosta-Alvear Lab!

Our lab seeks an in-depth understanding of the fundamental mechanisms by which cells respond to stress to preserve homeostasis. We approach this question using multiple levels of analysis, including biochemical, cell biology, molecular biology, and genomics/transcriptomics methods. Please check our Research section to learn more about our interests, our Lab Members section to meet our wonderful team, and our Publications section for a list of our work.

Recent News

  • Our fast and simple method to extract RNA, DNA and protein to facilitate detection of SARS-CoV-2 is published in the Journal of Clinical Microbiology!
  • Congratulations to Carlos, recipient of the 2020 UC MEXUS-CONACYT postdoctoral fellowship!
  • Preprint of our surveillance study on SARS-CoV-2 in a university population on MedRxiv
  • Our preprint on a fast and simple method to extract RNA, DNA and protein to facilitate detection of SARS-CoV-2

Selected Publications

  • The unfolded protein response and endoplasmic reticulum protein targeting machineries converge on the stress sensor IRE1.
  • A conformational RNA zipper promotes intron ejection during non-conventional XBP1 mRNA splicing.
  • Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits.
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Diego Acosta-Alvear Lab • Molecular, Cellular, and Developmental Biology • University of California, Santa Barbara
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