Title | AN AUTOMATIC FEATURE BASED MODEL FOR CELL SEGMENTATION FROM CONFOCAL MICROSCOPY VOLUMES. |
Publication Type | Journal Article |
Year of Publication | 2011 |
Authors | Delibaltov D, Ghosh P, Veeman M, Smith W, Manjunath BS |
Journal | Proc IEEE Int Symp Biomed Imaging |
Pagination | 199-203 |
Date Published | 2011 |
ISSN | 1945-7928 |
Abstract | We present a model for the automated segmentation of cells from confocal microscopy volumes of biological samples. The segmentation task for these images is exceptionally challenging due to weak boundaries and varying intensity during the imaging process. To tackle this, a two step pruning process based on the Fast Marching Method is first applied to obtain an over-segmented image. This is followed by a merging step based on an effective feature representation. The algorithm is applied on two different datasets: one from the ascidian Ciona and the other from the plant Arabidopsis. The presented 3D segmentation algorithm shows promising results on these datasets. |
Alternate Journal | Proc IEEE Int Symp Biomed Imaging |
PubMed ID | 23154829 |
PubMed Central ID | PMC3496755 |
Grant List | R01 HD059217 / HD / NICHD NIH HHS / United States |