How does something as complex, beautiful, and functional as an eye develop? How do neurons become precisely aligned and connected in intricate networks that allow vision and thought? And what goes awry in the case of neurodegenerative diseases? Finally, can stem cells be applied in novel therapies to treat such diseases, especially Age-related Macular Degeneration? These are the principal questions that drive our current research in the areas of stem cell research, neural development and neural disease.