Embryonic, induced pluripotent (iPS), and adult stem cells have great potential for treating a variety of diseases, including eye maladies such as macular degeneration.
We are interested in identifying and understanding the external molecular cues that guide the development of neurons. These include secreted extracellular matrix (ECM) molecules and cell surface molecules that influence cell fate, cell adhesion and migration, axon pathfinding, and synapse formation.