Publications

Found 53 results
Author Title Type [ Year(Desc)]
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2010
Gupta N, Lin BF, Campos LM, Dimitriou MD, Hikita ST, Treat ND, Tirrell MV, Clegg DO, Kramer EJ, Hawker CJ.  2010.  A versatile approach to high-throughput microarrays using thiol-ene chemistry. Nature Chemistry. 2(2):138-45.
2012
Piunova V, Patel P, Lee C, Tsie M, Grubbs RH, Clegg DO.  2012.  Biodegradable polymer scaffolds for stem-cell based treatment of age-related macular degeneration.
Hu Y, Liu L, Lu B, Zhu D, Ribeiro R, Diniz B, Thomas PB, Ahuja AK, Hinton DR, Tai Y-C et al..  2012.  A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic Research. 48(4):186-91.
Hu Y, Liu L, Lu B, Zhu D, Ribeiro R, Diniz B, Thomas PB, Ahuja AK, Hinton DR, Tai Y-C et al..  2012.  A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic Research. 48(4):186-91.
Gupta N, Lin BF, Campos LM, Dimitriou MD, Hikita ST, Treat ND, Tirrell MV, Clegg DO, Kramer EJ, Hawker CJ.  2012.  A versatile approach to high-throughput microarrays using thiol-ene chemistry. Nature Chemistry. 4:424–424.
2013
Clegg DO, Hikita ST, Hu Q, Buchholz DE, Rowland TJ, Conti L, Pennington B, Croze R, Leach L, Tsie M et al..  2013.  Derivation of retinal pigmented epithelial cells from pluripotent stem cells. The Stem Cell Handbook.
2014
Sowden J, Beebe D, Powell C, Bird A, Cepko C, Clegg DO, Gamm DA, Goldman D, Hitchcock P, Hyde D et al..  2014.  Restoring Vision to the Blind: The Lasker/IRRF Initiative for Innovation in Vision Science.. Transl Vis Sci Technol. 3(7):1.
2015
Leach LL, Buchholz DE, Nadar VP, Lowenstein SE, Clegg DO.  2015.  Canonical/β-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells. Investigative Ophthalmology & Visual Science. 56(2):1002-13.
Leach LL, Buchholz DE, Nadar VP, Lowenstein SE, Clegg DO.  2015.  Canonical/β-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells. Investigative Ophthalmology & Visual Science. 56(2):1002-13.
Leach LL, Clegg DO.  2015.  Concise Review: Making Stem Cells Retinal: Methods for Deriving Retinal Pigment Epithelium and Implications for Patients With Ocular Disease. Stem Cells. 33(8):2363-73.
Zhao T, Zhang Z-ning, Westenskow PD, Todorova D, Hu Z, Lin T, Rong Z, Kim J, He J, Wang M et al..  2015.  Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells. Cell Stem Cell. 17(3):353-9.
2016
Clevenger TN, Luna G, Boctor D, Fisher SK, Clegg DO.  2016.  Cell-mediated remodeling of biomimetic encapsulating hydrogels triggered by adipogenic differentiation of adipose stem cells. J Tissue Eng. 7:2041731416670482.
Leach LL, Croze RH, Hu Q, Nadar VP, Clevenger TN, Pennington BO, Gamm DM, Clegg DO.  2016.  Induced Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium: A Comparative Study Between Cell Lines and Differentiation Methods. J Ocul Pharmacol Ther. 32(5):317-30.
Huang X, Hu Q, Lai Y, Morales DP, Clegg DO, Reich NO.  2016.  Light-Patterned RNA Interference of 3D-Cultured Human Embryonic Stem Cells. Adv Mater. 28(48):10732-10737.
Clevenger TN, Luna G, Fisher SK, Clegg DO.  2016.  Strategies for bioengineered scaffolds that support adipose stem cells in regenerative therapies. Regenerative Medicine.
2017
Lin T-C, Seiler MJ, Zhu D, Falabella P, Hinton DR, Clegg DO, Humayun MS, Thomas BB.  2017.  Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models. Stem Cells Int. 2017:9428176.
Gornalusse GG, Hirata RK, Funk SE, Riolobos L, Lopes VS, Manske G, Prunkard D, Colunga AG, Hanafi L-A, Clegg DO et al..  2017.  HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells. Nat Biotechnol.
2018
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin C-M, Mitra D, Zhu D, Thomas BB et al..  2018.  A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration.. Science Translational Medicine. 10(435)
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin C-M, Mitra D, Zhu D, Thomas BB et al..  2018.  A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration.. Science Translational Medicine. 10(435)
2019
Toh H, Smolentsev A, Bozadjian RV, Keeley PW, Lockwood MD, Sadjadi R, Clegg DO, Blodi BA, Coffey PJ, Reese BE et al..  2019.  Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat.. Lab Invest. 99(10):1547-1560.
2020
Lin TC, Stevanovic M, Foltz LP, Clegg DO, Humayun MS.  2020.  Stem Cell-Derived Retinal Cells for Transplantation. Macular Surgery,. :423-437.
Kashani AH, Uang J, Mert M, Rahhal F, Chan C, Avery RL, Dugel P, Chen S, Lebkowski J, Clegg DO et al..  2020.  Surgical Method for Implantation of a Biosynthetic Retinal Pigment Epithelium Monolayer for Geographic Atrophy: Experience from a Phase 1/2a Study.. Ophthalmol Retina. 4(3):264-273.
2021
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Chen S, Chan C, Palejwala N, Ingram A, Dang W et al..  2021.  One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration.. Transl Vis Sci Technol. 10(10):13.
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Chen S, Chan C, Palejwala N, Ingram A, Dang W et al..  2021.  One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration.. Transl Vis Sci Technol. 10(10):13.
Pennington BO, Bailey JK, Faynus MA, Hinman C, Hee MN, Ritts R, Nadar V, Zhu D, Mitra D, Martinez-Camarillo JCarlos et al..  2021.  Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo.. Sci Rep. 11(1):6286.

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