Publications

Found 31 results
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2022
Kashani AH, Lebkowski JS, Hinton DR, Zhu D, Faynus MA, Chen S, Rahhal FM, Avery RL, Salehi-Had H, Chan C et al..  2022.  Survival of an HLA-mismatched, bioengineered RPE implant in dry age-related macular degeneration.. Stem Cell Reports. 17(3):448-458.
Kashani AH, Lebkowski JS, Hinton DR, Zhu D, Faynus MA, Chen S, Rahhal FM, Avery RL, Salehi-Had H, Chan C et al..  2022.  Survival of an HLA-mismatched, bioengineered RPE implant in dry age-related macular degeneration.. Stem Cell Reports. 17(3):448-458.
2021
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Chen S, Chan C, Palejwala N, Ingram A, Dang W et al..  2021.  One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration.. Transl Vis Sci Technol. 10(10):13.
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Chen S, Chan C, Palejwala N, Ingram A, Dang W et al..  2021.  One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration.. Transl Vis Sci Technol. 10(10):13.
Pennington BO, Bailey JK, Faynus MA, Hinman C, Hee MN, Ritts R, Nadar V, Zhu D, Mitra D, Martinez-Camarillo JCarlos et al..  2021.  Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo.. Sci Rep. 11(1):6286.
2018
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin C-M, Mitra D, Zhu D, Thomas BB et al..  2018.  A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration.. Science Translational Medicine. 10(435)
2017
Siegel KR, Clevenger TN, Clegg DO, Proctor DA, Proctor CS.  2017.  Adipose Stem Cells Incorporated in Fibrin Clot Modulate Expression of Growth Factors. Arthroscopy.
Siegel KR, Clevenger TN, Clegg DO, Proctor DA, Proctor CS.  2017.  Adipose Stem Cells Incorporated in Fibrin Clot Modulate Expression of Growth Factors. Arthroscopy.
Gornalusse GG, Hirata RK, Funk SE, Riolobos L, Lopes VS, Manske G, Prunkard D, Colunga AG, Hanafi L-A, Clegg DO et al..  2017.  HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells. Nat Biotechnol.
2016
Leach LL, Croze RH, Hu Q, Nadar VP, Clevenger TN, Pennington BO, Gamm DM, Clegg DO.  2016.  Induced Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium: A Comparative Study Between Cell Lines and Differentiation Methods. J Ocul Pharmacol Ther. 32(5):317-30.
Pennington BO, Clegg DO.  2016.  Pluripotent Stem Cell-Based Therapies in Combination with Substrate for the Treatment of Age-Related Macular Degeneration. Journal of Ocular Pharmacology & Therapeutics.
Koss MJ, Falabella P, Stefanini FR, Pfister M, Thomas BB, Kashani AH, Brant R, Zhu D, Clegg DO, Hinton DR et al..  2016.  Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs. Graefes Arch Clin Exp Ophthalmol. 254(8):1553-65.
2015
Pennington BO, Clegg DO, Melkoumian ZK, Hikita ST.  2015.  Defined culture of human embryonic stem cells and xeno-free derivation of retinal pigmented epithelial cells on a novel, synthetic substrate. Stem Cells Translational Medicine. 4(2):165-77.
Huang X, Hu Q, Braun GB, Pallaoro A, Morales DP, Zasadzinski J, Clegg DO, Reich NO.  2015.  Light-activated RNA interference in human embryonic stem cells. Biomaterials. 63:70-9.
2014
Pennington BO, Sears D, Clegg DO.  2014.  Interactive Hangman teaches amino acid structures and abbreviations. Biochemistry & Moleluclar Biology Education. 42(6):495-500.
Sowden J, Beebe D, Powell C, Bird A, Cepko C, Clegg DO, Gamm DA, Goldman D, Hitchcock P, Hyde D et al..  2014.  Restoring Vision to the Blind: The Lasker/IRRF Initiative for Innovation in Vision Science.. Transl Vis Sci Technol. 3(7):1.
2013
Clegg DO, Hikita ST, Hu Q, Buchholz DE, Rowland TJ, Conti L, Pennington B, Croze R, Leach L, Tsie M et al..  2013.  Derivation of retinal pigmented epithelial cells from pluripotent stem cells. The Stem Cell Handbook.
Hikita S, Clegg D, Johnson L, Miller L, Tsie M, Presbrey C, Conti L, Maloney M, Hinton D, Hu Q et al..  2013.  Methods of Culturing Retinal Pigmented Epithelium Cells, Including Xeno-Free Production, RPE Enrichment, and Cryopreservation.
Pennington BOcean, Buchholz DE, Hinman C, Croze R, Coffey PJ, Clegg DO.  2013.  Rapid and efficient derivation of retinal pigment epithelium (RPE) from human pluripotent stem cells. FASEB Journal. 27
Buchholz DE, Pennington BO, Croze RH, Hinman CR, Coffey PJ, Clegg DO.  2013.  Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium. Stem Cells Translational Medicine. 2(5):384-93.
2012
Piunova V, Patel P, Lee C, Tsie M, Grubbs RH, Clegg DO.  2012.  Biodegradable polymer scaffolds for stem-cell based treatment of age-related macular degeneration.
Piunova V, Patel P, Lee C, Tsie M, Grubbs RH, Clegg DO.  2012.  Biodegradable polymer scaffolds for stem-cell based treatment of age-related macular degeneration.
2010
Neveu P, Kye MJeong, Qi S, Buchholz DE, Clegg DO, Sahin M, Park I-H, Kim K-S, Daley GQ, Kornblum HI et al..  2010.  MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states. Cell Stem Cell. 7(6):671-81.
2005
Putzke AP, Hikita ST, Clegg DO, Rothman JH.  2005.  Essential kinase-independent role of a Fer-like non-receptor tyrosine kinase in Caenorhabditis elegans morphogenesis. Development. 132(14):3185-95.
2004
Leu ST, Jacques SAL, Wingerd KL, Hikita ST, Tolhurst EC, Pring JL, Wiswell D, Kinney L, Goodman NL, Jackson DY et al..  2004.  Integrin alpha4beta1 function is required for cell survival in developing retina. Developmental Biology. 276(2):416-30.

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