Publications

Found 37 results
Author Title Type [ Year(Asc)]
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2021
Pennington BO, Bailey JK, Faynus MA, Hinman C, Hee MN, Ritts R, Nadar V, Zhu D, Mitra D, Martinez-Camarillo JCarlos et al..  2021.  Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo.. Sci Rep. 11(1):6286.
2019
Toh H, Smolentsev A, Bozadjian RV, Keeley PW, Lockwood MD, Sadjadi R, Clegg DO, Blodi BA, Coffey PJ, Reese BE et al..  2019.  Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat.. Lab Invest. 99(10):1547-1560.
Toh H, Smolentsev A, Bozadjian RV, Keeley PW, Lockwood MD, Sadjadi R, Clegg DO, Blodi BA, Coffey PJ, Reese BE et al..  2019.  Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat.. Lab Invest. 99(10):1547-1560.
2018
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin C-M, Mitra D, Zhu D, Thomas BB et al..  2018.  A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration.. Science Translational Medicine. 10(435)
Foltz LP, Howden SE, Thomson JA, Clegg DO.  2018.  Functional Assessment of Patient-Derived Retinal Pigment Epithelial Cells Edited by CRISPR/Cas9.. Int J Mol Sci. 19(12)
2017
Lin T-C, Seiler MJ, Zhu D, Falabella P, Hinton DR, Clegg DO, Humayun MS, Thomas BB.  2017.  Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models. Stem Cells Int. 2017:9428176.
Gornalusse GG, Hirata RK, Funk SE, Riolobos L, Lopes VS, Manske G, Prunkard D, Colunga AG, Hanafi L-A, Clegg DO et al..  2017.  HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells. Nat Biotechnol.
2016
Croze RH, Thi WJ, Clegg DO.  2016.  ROCK Inhibition Promotes Attachment, Proliferation, and Wound Closure in Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium. Transl Vis Sci Technol. 5(6):7.
Koss MJ, Falabella P, Stefanini FR, Pfister M, Thomas BB, Kashani AH, Brant R, Zhu D, Clegg DO, Hinton DR et al..  2016.  Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs. Graefes Arch Clin Exp Ophthalmol. 254(8):1553-65.
Thomas BB, Zhu D, Zhang L, Thomas PB, Hu Y, Nazari H, Stefanini F, Falabella P, Clegg DO, Hinton DR et al..  2016.  Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats. Invest Ophthalmol Vis Sci. 57(6):2877-87.
Thomas BB, Zhu D, Zhang L, Thomas PB, Hu Y, Nazari H, Stefanini F, Falabella P, Clegg DO, Hinton DR et al..  2016.  Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats. Invest Ophthalmol Vis Sci. 57(6):2877-87.
2015
Zhao T, Zhang Z-ning, Westenskow PD, Todorova D, Hu Z, Lin T, Rong Z, Kim J, He J, Wang M et al..  2015.  Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells. Cell Stem Cell. 17(3):353-9.
2014
Hu Q, Chen R, Teesalu T, Ruoslahti E, Clegg DO.  2014.  Reprogramming human retinal pigmented epithelial cells to neurons using recombinant proteins. Stem Cells Translational Medicine. 3(12):1526-34.
Croze RH, Buchholz DE, Radeke MJ, Thi WJ, Hu Q, Coffey PJ, Clegg DO.  2014.  ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium. Stem Cells Translational Medicine. 3(9):1066-78.
2013
Clegg DO, Hikita ST, Hu Q, Buchholz DE, Rowland TJ, Conti L, Pennington B, Croze R, Leach L, Tsie M et al..  2013.  Derivation of retinal pigmented epithelial cells from pluripotent stem cells. The Stem Cell Handbook.
Hikita S, Clegg D, Johnson L, Miller L, Tsie M, Presbrey C, Conti L, Maloney M, Hinton D, Hu Q et al..  2013.  Methods of Culturing Retinal Pigmented Epithelium Cells, Including Xeno-Free Production, RPE Enrichment, and Cryopreservation.
2012
Piunova V, Patel P, Lee C, Tsie M, Grubbs RH, Clegg DO.  2012.  Biodegradable polymer scaffolds for stem-cell based treatment of age-related macular degeneration.
Hu Y, Liu L, Lu B, Zhu D, Ribeiro R, Diniz B, Thomas PB, Ahuja AK, Hinton DR, Tai Y-C et al..  2012.  A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic Research. 48(4):186-91.
Hu Y, Liu L, Lu B, Zhu D, Ribeiro R, Diniz B, Thomas PB, Ahuja AK, Hinton DR, Tai Y-C et al..  2012.  A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic Research. 48(4):186-91.
Hu Y, Liu L, Lu B, Zhu D, Ribeiro R, Diniz B, Thomas PB, Ahuja AK, Hinton DR, Tai Y-C et al..  2012.  A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic Research. 48(4):186-91.
Gupta N, Lin BF, Campos LM, Dimitriou MD, Hikita ST, Treat ND, Tirrell MV, Clegg DO, Kramer EJ, Hawker CJ.  2012.  A versatile approach to high-throughput microarrays using thiol-ene chemistry. Nature Chemistry. 4:424–424.
Gupta N, Lin BF, Campos LM, Dimitriou MD, Hikita ST, Treat ND, Tirrell MV, Clegg DO, Kramer EJ, Hawker CJ.  2012.  A versatile approach to high-throughput microarrays using thiol-ene chemistry. Nature Chemistry. 4:424–424.
2011
Ahuja A, Clegg D, Grubbs R, Hinton D, Humayun M, Tai YC.  2011.  Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same.
Humayun M, Ahuja A, Tai Y-C, Hinton D, Grubbs R, Clegg D, JOHNSON LVallance, Hikita ST, .  2011.  Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same.
2010
Gupta N, Lin BF, Campos LM, Dimitriou MD, Hikita ST, Treat ND, Tirrell MV, Clegg DO, Kramer EJ, Hawker CJ.  2010.  A versatile approach to high-throughput microarrays using thiol-ene chemistry. Nature Chemistry. 2(2):138-45.

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