Publications

Found 125 results
Author Title [ Type(Desc)] Year
Journal Article
Clegg DO, Koshland DE.  1984.  The role of a signaling protein in bacterial sensing: behavioral effects of increased gene expression. Proceedings of the National Academy of Sciences. 81(16):5056-60.
Rowland TJ, Miller LM, Blaschke AJ, E Doss L, Bonham AJ, Hikita ST, Johnson LV, Clegg DO.  2010.  Roles of integrins in human induced pluripotent stem cell growth on Matrigel and vitronectin. Stem Cells & Development. 19(8):1231-40.
Nazari H, Zhang L, Zhu D, Chader GJ, Falabella P, Stefanini F, Rowland T, Clegg DO, Kashani AH, Hinton DR et al..  2015.  Stem cell based therapies for age-related macular degeneration: The promises and the challenges. Progress in Retinal & Eye Research. 48:1-39.
Buchholz DE, Hikita ST, Radeke MJ, Blashke KE, Johnson LV, Clegg DO.  2008.  Stem cell derived retinal pigment Epithelium for the treatment of age-related Macular degeneration. Journal of Vision. 8:47–47.
Clevenger TN, Luna G, Fisher SK, Clegg DO.  2016.  Strategies for bioengineered scaffolds that support adipose stem cells in regenerative therapies. Regenerative Medicine.
Chen CH, Clegg DO, Hansma HG.  1998.  Structures and dynamic motion of laminin-1 as observed by atomic force microscopy. Biochemistry. 37(22):8262-7.
Koss MJ, Falabella P, Stefanini FR, Pfister M, Thomas BB, Kashani AH, Brant R, Zhu D, Clegg DO, Hinton DR et al..  2016.  Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs. Graefes Arch Clin Exp Ophthalmol. 254(8):1553-65.
Kashani AH, Uang J, Mert M, Rahhal F, Chan C, Avery RL, Dugel P, Chen S, Lebkowski J, Clegg DO et al..  2020.  Surgical Method for Implantation of a Biosynthetic Retinal Pigment Epithelium Monolayer for Geographic Atrophy: Experience from a Phase 1/2a Study.. Ophthalmol Retina. 4(3):264-273.
Thomas BB, Zhu D, Zhang L, Thomas PB, Hu Y, Nazari H, Stefanini F, Falabella P, Clegg DO, Hinton DR et al..  2016.  Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats. Invest Ophthalmol Vis Sci. 57(6):2877-87.
Kashani AH, Lebkowski JS, Hinton DR, Zhu D, Faynus MA, Chen S, Rahhal FM, Avery RL, Salehi-Had H, Chan C et al..  2022.  Survival of an HLA-mismatched, bioengineered RPE implant in dry age-related macular degeneration.. Stem Cell Reports. 17(3):448-458.
Kolhar P, Kotamraju VRamana, Hikita ST, Clegg DO, Ruoslahti E.  2010.  Synthetic surfaces for human embryonic stem cell culture. Journal of Biotechnology. 146(3):143-6.
Wang EA, Mowry KL, Clegg DO, Koshland DE.  1982.  Tandem duplication and multiple functions of a receptor gene in bacterial chemotaxis. Journal of Biological Chemistry. 257(9):4673-6.
Gervin DB, Cann GM, Clegg DO.  1996.  Temporal and spatial regulation of integrin vitronectin receptor mRNAs in the embryonic chick retina. Investigative Ophthalmology & Visual Science. 37(6):1084-96.
Dunkle ETolhurst, Zaucke F, Clegg DO.  2007.  Thrombospondin-4 and matrix three-dimensionality in axon outgrowth and adhesion in the developing retina. Expierimental Eye Research. 84(4):707-17.
Tolhurst EC, Zaucke F, Clegg DO.  2004.  Thrombospondin-4 is Expressed in Embryonic Mouse Retina and Supports Integrin-Dependent Neurite Outgrowth. Investigative Ophtalmology & Visual Science. 45:5348.
Toh H, Smolentsev A, Bozadjian RV, Keeley PW, Lockwood MD, Sadjadi R, Clegg DO, Blodi BA, Coffey PJ, Reese BE et al..  2019.  Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat.. Lab Invest. 99(10):1547-1560.
Mey A, Gandrillon O, McNagny KM, Clegg DO, Samarut J.  2002.  The v-erbA oncogene blocks expression of alpha2/beta1 integrin a normal inhibitor of erythroid progenitor proliferation. Oncogene. 21(18):2864-72.
Gupta N, Lin BF, Campos LM, Dimitriou MD, Hikita ST, Treat ND, Tirrell MV, Clegg DO, Kramer EJ, Hawker CJ.  2012.  A versatile approach to high-throughput microarrays using thiol-ene chemistry. Nature Chemistry. 4:424–424.
Gupta N, Lin BF, Campos LM, Dimitriou MD, Hikita ST, Treat ND, Tirrell MV, Clegg DO, Kramer EJ, Hawker CJ.  2010.  A versatile approach to high-throughput microarrays using thiol-ene chemistry. Nature Chemistry. 2(2):138-45.
Clevenger TN, Hinman CR, Rubin RKAshley, Smither K, Burke DJ, Hawker CJ, Messina D, Van Epps D, Clegg DO.  2016.  Vitronectin-Based, Biomimetic Encapsulating Hydrogel Scaffolds Support Adipogenesis of Adipose Stem Cells. Tissue Engineering Part A. 22(7-8):597-609.
Cann GM, Bradshaw AD, Gervin DB, Hunter AW, Clegg DO.  1996.  Widespread expression of beta1 integrins in the developing chick retina: evidence for a role in migration of retinal ganglion cells. Developmental Biology. 180(1):82-96.
Pennington BO, Bailey JK, Faynus MA, Hinman C, Hee MN, Ritts R, Nadar V, Zhu D, Mitra D, Martinez-Camarillo JCarlos et al..  2021.  Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo.. Sci Rep. 11(1):6286.
Miscellaneous
Ahuja A, Clegg D, Grubbs R, Hinton D, Humayun M, Tai YC.  2011.  Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same.
Humayun M, Ahuja A, Tai Y-C, Hinton D, Grubbs R, Clegg D, JOHNSON LVallance, Hikita ST, .  2011.  Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same.
Hikita S, Clegg D, Johnson L, Miller L, Tsie M, Presbrey C, Conti L, Maloney M, Hinton D, Hu Q et al..  2013.  Methods of Culturing Retinal Pigmented Epithelium Cells, Including Xeno-Free Production, RPE Enrichment, and Cryopreservation.

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