Evolutionary and Quantitative Genetics

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Researchers

Joel Rothman

Regulation of development and differentiation; regulation of programmed cell death and cell division; mechanisms of tumorigenesis

Juwel Chandra Baray

My research is centered on understanding transdifferentiation, transorganogenesis, and the intriguing fields of aging and longevity in the nematode C. elegans. Furthermore, my objective is to bridge the gap between human biology and model organisms by applying these insights to the context of human cells.

Anna Jellema-Butler

I am interested in understanding the mechanisms controlling healthspan and lifespan, including the role of genetic and epigenetic factors, natural and artificial rejuvenation events, and dietary and behavioral interventions. I work with the premier aging model of C. elegans and focus on leveraging large-scale biological data through the use of statistics and bioinformatics. 

Sierra Klier

My research focuses on transcriptomic analysis of the processes we study in the lab. In particular, I am interested in changes in gene regulation during recovery from extreme stress in tardigrades, as well as the transcriptional changes in C. Elegans as they undergo transdifferentiation.

Nikolas Belle

I work with Sierra Klier on using machine learning models for genome annotation of tardigrades. We are particularly interested in using these models to uncover the genetic mechanisms behind tardigrade extremotolerance.

Research Collaborators

University of Canterbury, New Zealand