We are studying how developing cells become committed to specific differentiated cell types and how we can unlock that commitment and reprogram them to adopt new identities.
We are investigating the control systems that ensure that cells undergo division and programmed death at the appropriate time and location, processes that are critical in cancer biology.
We are examining the mechanisms that correct errors in development and studying how animals ensure faithful transmission of mitochondrial genomes across generations.
We are investigating how gene regulatory networks that drive developmental processes change during animal evolution, resulting in innovations in their architecture.
In collaboration with Prof. Phil Lubin’s group, we are developing systems and methods for adapting microscopic animals, including C. elegans and tardigrades, to interstellar travel.