Publications

Found 42 results
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2022
Kashani AH, Lebkowski JS, Hinton DR, Zhu D, Faynus MA, Chen S, Rahhal FM, Avery RL, Salehi-Had H, Chan C et al..  2022.  Survival of an HLA-mismatched, bioengineered RPE implant in dry age-related macular degeneration.. Stem Cell Reports. 17(3):448-458.
2021
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Chen S, Chan C, Palejwala N, Ingram A, Dang W et al..  2021.  One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration.. Transl Vis Sci Technol. 10(10):13.
Pennington BO, Bailey JK, Faynus MA, Hinman C, Hee MN, Ritts R, Nadar V, Zhu D, Mitra D, Martinez-Camarillo JCarlos et al..  2021.  Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo.. Sci Rep. 11(1):6286.
2019
Toh H, Smolentsev A, Bozadjian RV, Keeley PW, Lockwood MD, Sadjadi R, Clegg DO, Blodi BA, Coffey PJ, Reese BE et al..  2019.  Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat.. Lab Invest. 99(10):1547-1560.
Toh H, Smolentsev A, Bozadjian RV, Keeley PW, Lockwood MD, Sadjadi R, Clegg DO, Blodi BA, Coffey PJ, Reese BE et al..  2019.  Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat.. Lab Invest. 99(10):1547-1560.
2016
Clevenger TN, Luna G, Boctor D, Fisher SK, Clegg DO.  2016.  Cell-mediated remodeling of biomimetic encapsulating hydrogels triggered by adipogenic differentiation of adipose stem cells. J Tissue Eng. 7:2041731416670482.
Koss MJ, Falabella P, Stefanini FR, Pfister M, Thomas BB, Kashani AH, Brant R, Zhu D, Clegg DO, Hinton DR et al..  2016.  Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs. Graefes Arch Clin Exp Ophthalmol. 254(8):1553-65.
Clevenger TN, Hinman CR, Rubin RKAshley, Smither K, Burke DJ, Hawker CJ, Messina D, Van Epps D, Clegg DO.  2016.  Vitronectin-Based, Biomimetic Encapsulating Hydrogel Scaffolds Support Adipogenesis of Adipose Stem Cells. Tissue Engineering Part A. 22(7-8):597-609.
2015
Leach LL, Buchholz DE, Nadar VP, Lowenstein SE, Clegg DO.  2015.  Canonical/β-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells. Investigative Ophthalmology & Visual Science. 56(2):1002-13.
Huang X, Hu Q, Braun GB, Pallaoro A, Morales DP, Zasadzinski J, Clegg DO, Reich NO.  2015.  Light-activated RNA interference in human embryonic stem cells. Biomaterials. 63:70-9.
2014
Sowden J, Beebe D, Powell C, Bird A, Cepko C, Clegg DO, Gamm DA, Goldman D, Hitchcock P, Hyde D et al..  2014.  Restoring Vision to the Blind: The Lasker/IRRF Initiative for Innovation in Vision Science.. Transl Vis Sci Technol. 3(7):1.
Sowden J, Beebe D, Powell C, Bird A, Cepko C, Clegg DO, Gamm DA, Goldman D, Hitchcock P, Hyde D et al..  2014.  Restoring Vision to the Blind: The Lasker/IRRF Initiative for Innovation in Vision Science.. Transl Vis Sci Technol. 3(7):1.
Croze RH, Buchholz DE, Radeke MJ, Thi WJ, Hu Q, Coffey PJ, Clegg DO.  2014.  ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium. Stem Cells Translational Medicine. 3(9):1066-78.
2013
Clegg DO, Hikita ST, Hu Q, Buchholz DE, Rowland TJ, Conti L, Pennington B, Croze R, Leach L, Tsie M et al..  2013.  Derivation of retinal pigmented epithelial cells from pluripotent stem cells. The Stem Cell Handbook.
Rowland TJ, Blaschke AJ, Buchholz DE, Hikita ST, Johnson LV, Clegg DO.  2013.  Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins. Journal of Tissue Engineering and Regenerative Medicine. 7(8):642-53.
Rowland TJ, Blaschke AJ, Buchholz DE, Hikita ST, Johnson LV, Clegg DO.  2013.  Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins. Journal of Tissue Engineering and Regenerative Medicine. 7(8):642-53.
Pennington BOcean, Buchholz DE, Hinman C, Croze R, Coffey PJ, Clegg DO.  2013.  Rapid and efficient derivation of retinal pigment epithelium (RPE) from human pluripotent stem cells. FASEB Journal. 27
Buchholz DE, Pennington BO, Croze RH, Hinman CR, Coffey PJ, Clegg DO.  2013.  Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium. Stem Cells Translational Medicine. 2(5):384-93.
2012
Rowland TJ, Buchholz DE, Clegg DO.  2012.  Pluripotent human stem cells for the treatment of retinal disease. Journal of Cellular Physiology. 227(2):457-66.
2010
Neveu P, Kye MJeong, Qi S, Buchholz DE, Clegg DO, Sahin M, Park I-H, Kim K-S, Daley GQ, Kornblum HI et al..  2010.  MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states. Cell Stem Cell. 7(6):671-81.
Rowland TJ, Miller LM, Blaschke AJ, E Doss L, Bonham AJ, Hikita ST, Johnson LV, Clegg DO.  2010.  Roles of integrins in human induced pluripotent stem cell growth on Matrigel and vitronectin. Stem Cells & Development. 19(8):1231-40.
Rowland TJ, Miller LM, Blaschke AJ, E Doss L, Bonham AJ, Hikita ST, Johnson LV, Clegg DO.  2010.  Roles of integrins in human induced pluripotent stem cell growth on Matrigel and vitronectin. Stem Cells & Development. 19(8):1231-40.
2009
Buchholz DE, Hikita ST, Rowland TJ, Friedrich AM, Hinman CR, Johnson LV, Clegg DO.  2009.  Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells. Stem Cells. 27(10):2427-34.
Carr A-J, Vugler AA, Hikita ST, Lawrence JM, Gias C, Chen LLi, Buchholz DE, Ahmado A, Semo M'ayan, Smart MJK et al..  2009.  Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat. PLoS One. 4(12):e8152.
2008
Hikita ST, Kosik KS, Clegg DO, Bamdad C.  2008.  MUC1* mediates the growth of human pluripotent stem cells. PLoS One. 3(10):e3312.

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