Publications

Found 24 results
Author Title Type [ Year(Asc)]
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2022
Faynus MA, Clegg DO.  2022.  Modeling inherited retinal dystrophies using induced pluripotent stem cells. Current Progress in iPSC Disease Modeling. 14:157-184.
Kashani AH, Lebkowski JS, Hinton DR, Zhu D, Faynus MA, Chen S, Rahhal FM, Avery RL, Salehi-Had H, Chan C et al..  2022.  Survival of an HLA-mismatched, bioengineered RPE implant in dry age-related macular degeneration.. Stem Cell Reports. 17(3):448-458.
2021
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Chen S, Chan C, Palejwala N, Ingram A, Dang W et al..  2021.  One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration.. Transl Vis Sci Technol. 10(10):13.
Pennington BO, Bailey JK, Faynus MA, Hinman C, Hee MN, Ritts R, Nadar V, Zhu D, Mitra D, Martinez-Camarillo JCarlos et al..  2021.  Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo.. Sci Rep. 11(1):6286.
2020
Lin TC, Stevanovic M, Foltz LP, Clegg DO, Humayun MS.  2020.  Stem Cell-Derived Retinal Cells for Transplantation. Macular Surgery,. :423-437.
2018
Foltz LP, Howden SE, Thomson JA, Clegg DO.  2018.  Functional Assessment of Patient-Derived Retinal Pigment Epithelial Cells Edited by CRISPR/Cas9.. Int J Mol Sci. 19(12)
Foltz LP, Clegg DO.  2018.  Patient-derived induced pluripotent stem cells for modelling genetic retinal dystrophies.. Progress in Retinal and Eye Research.
2017
Lin T-C, Seiler MJ, Zhu D, Falabella P, Hinton DR, Clegg DO, Humayun MS, Thomas BB.  2017.  Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models. Stem Cells Int. 2017:9428176.
Gornalusse GG, Hirata RK, Funk SE, Riolobos L, Lopes VS, Manske G, Prunkard D, Colunga AG, Hanafi L-A, Clegg DO et al..  2017.  HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells. Nat Biotechnol.
Foltz LP, Clegg DO.  2017.  Rapid, Directed Differentiation of Retinal Pigment Epithelial Cells from Human Embryonic or Induced Pluripotent Stem Cells. J Vis Exp. (128)
Rowland TJ, Hinton DR, Freidlander M, Gamm D, Clegg DO.  2017.  Stem Cells and Cellular Therapy. Ryan's Retina.
2016
Clevenger TN, Luna G, Boctor D, Fisher SK, Clegg DO.  2016.  Cell-mediated remodeling of biomimetic encapsulating hydrogels triggered by adipogenic differentiation of adipose stem cells. J Tissue Eng. 7:2041731416670482.
Fernandes RABrant, Koss MJanusz, Falabella P, Stefanini FRosa, Maia M, Diniz B, Ribeiro R, Hu Y, Hinton D, Clegg DO et al..  2016.  An Innovative Surgical Technique for Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium in Yucatan Mini Pigs: Preliminary Results. Ophthalmic Surgery, Lasers Imaging Retina. 47(4):342-51.
Fernandes RABrant, Koss MJanusz, Falabella P, Stefanini FRosa, Maia M, Diniz B, Ribeiro R, Hu Y, Hinton D, Clegg DO et al..  2016.  An Innovative Surgical Technique for Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium in Yucatan Mini Pigs: Preliminary Results. Ophthalmic Surgery, Lasers Imaging Retina. 47(4):342-51.
Clevenger TN, Luna G, Fisher SK, Clegg DO.  2016.  Strategies for bioengineered scaffolds that support adipose stem cells in regenerative therapies. Regenerative Medicine.
Koss MJ, Falabella P, Stefanini FR, Pfister M, Thomas BB, Kashani AH, Brant R, Zhu D, Clegg DO, Hinton DR et al..  2016.  Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs. Graefes Arch Clin Exp Ophthalmol. 254(8):1553-65.
Thomas BB, Zhu D, Zhang L, Thomas PB, Hu Y, Nazari H, Stefanini F, Falabella P, Clegg DO, Hinton DR et al..  2016.  Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats. Invest Ophthalmol Vis Sci. 57(6):2877-87.
2015
Forest DL, Johnson LV, Clegg DO.  2015.  Cellular models and therapies for age-related macular degeneration. Disease Models & Mechanisms. 8(5):421-7.
Zhao T, Zhang Z-ning, Westenskow PD, Todorova D, Hu Z, Lin T, Rong Z, Kim J, He J, Wang M et al..  2015.  Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells. Cell Stem Cell. 17(3):353-9.
Nazari H, Zhang L, Zhu D, Chader GJ, Falabella P, Stefanini F, Rowland T, Clegg DO, Kashani AH, Hinton DR et al..  2015.  Stem cell based therapies for age-related macular degeneration: The promises and the challenges. Progress in Retinal & Eye Research. 48:1-39.
2010
Hu Q, Friedrich AM, Johnson LV, Clegg DO.  2010.  Memory in induced pluripotent stem cells: reprogrammed human retinal-pigmented epithelial cells show tendency for spontaneous redifferentiation. Stem Cells. 28(11):1981-91.
2009
Buchholz DE, Hikita ST, Rowland TJ, Friedrich AM, Hinman CR, Johnson LV, Clegg DO.  2009.  Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells. Stem Cells. 27(10):2427-34.
1998
Setty S, Kim Y, Fields GB, Clegg DO, Wayner EA, Tsilibary EC.  1998.  Interactions of type IV collagen and its domains with human mesangial cells. Journal of Biological Chemistry. 273(20):12244-9.
1990
Muller SR, Sullivan PD, Clegg DO, Feinstein SC.  1990.  Efficient transfection and expression of heterologous genes in PC12 cells. DNA Cell Biology. 9(3):221-9.