Publications

Found 25 results
Author Title Type [ Year(Asc)]
Filters: Author is Clegg, Dennis O and Keyword is Humans  [Clear All Filters]
2022
Kashani AH, Lebkowski JS, Hinton DR, Zhu D, Faynus MA, Chen S, Rahhal FM, Avery RL, Salehi-Had H, Chan C et al..  2022.  Survival of an HLA-mismatched, bioengineered RPE implant in dry age-related macular degeneration.. Stem Cell Reports. 17(3):448-458.
2021
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Chen S, Chan C, Palejwala N, Ingram A, Dang W et al..  2021.  One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration.. Transl Vis Sci Technol. 10(10):13.
Pennington BO, Bailey JK, Faynus MA, Hinman C, Hee MN, Ritts R, Nadar V, Zhu D, Mitra D, Martinez-Camarillo JCarlos et al..  2021.  Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo.. Sci Rep. 11(1):6286.
2020
Kashani AH, Uang J, Mert M, Rahhal F, Chan C, Avery RL, Dugel P, Chen S, Lebkowski J, Clegg DO et al..  2020.  Surgical Method for Implantation of a Biosynthetic Retinal Pigment Epithelium Monolayer for Geographic Atrophy: Experience from a Phase 1/2a Study.. Ophthalmol Retina. 4(3):264-273.
2015
Leach LL, Buchholz DE, Nadar VP, Lowenstein SE, Clegg DO.  2015.  Canonical/β-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells. Investigative Ophthalmology & Visual Science. 56(2):1002-13.
Pennington BO, Clegg DO, Melkoumian ZK, Hikita ST.  2015.  Defined culture of human embryonic stem cells and xeno-free derivation of retinal pigmented epithelial cells on a novel, synthetic substrate. Stem Cells Translational Medicine. 4(2):165-77.
2014
Croze RH, Clegg DO.  2014.  Differentiation of pluripotent stem cells into retinal pigmented epithelium. Developments in Ophthalmology. 53:81-96.
Pennington BO, Sears D, Clegg DO.  2014.  Interactive Hangman teaches amino acid structures and abbreviations. Biochemistry & Moleluclar Biology Education. 42(6):495-500.
Hu Q, Chen R, Teesalu T, Ruoslahti E, Clegg DO.  2014.  Reprogramming human retinal pigmented epithelial cells to neurons using recombinant proteins. Stem Cells Translational Medicine. 3(12):1526-34.
Croze RH, Buchholz DE, Radeke MJ, Thi WJ, Hu Q, Coffey PJ, Clegg DO.  2014.  ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium. Stem Cells Translational Medicine. 3(9):1066-78.
2013
Rowland TJ, Blaschke AJ, Buchholz DE, Hikita ST, Johnson LV, Clegg DO.  2013.  Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins. Journal of Tissue Engineering and Regenerative Medicine. 7(8):642-53.
Buchholz DE, Pennington BO, Croze RH, Hinman CR, Coffey PJ, Clegg DO.  2013.  Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium. Stem Cells Translational Medicine. 2(5):384-93.
2012
Hu Y, Liu L, Lu B, Zhu D, Ribeiro R, Diniz B, Thomas PB, Ahuja AK, Hinton DR, Tai Y-C et al..  2012.  A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic Research. 48(4):186-91.
Rowland TJ, Buchholz DE, Clegg DO.  2012.  Pluripotent human stem cells for the treatment of retinal disease. Journal of Cellular Physiology. 227(2):457-66.
2010
Hu Q, Friedrich AM, Johnson LV, Clegg DO.  2010.  Memory in induced pluripotent stem cells: reprogrammed human retinal-pigmented epithelial cells show tendency for spontaneous redifferentiation. Stem Cells. 28(11):1981-91.
Neveu P, Kye MJeong, Qi S, Buchholz DE, Clegg DO, Sahin M, Park I-H, Kim K-S, Daley GQ, Kornblum HI et al..  2010.  MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states. Cell Stem Cell. 7(6):671-81.
Rowland TJ, Miller LM, Blaschke AJ, E Doss L, Bonham AJ, Hikita ST, Johnson LV, Clegg DO.  2010.  Roles of integrins in human induced pluripotent stem cell growth on Matrigel and vitronectin. Stem Cells & Development. 19(8):1231-40.
Kolhar P, Kotamraju VRamana, Hikita ST, Clegg DO, Ruoslahti E.  2010.  Synthetic surfaces for human embryonic stem cell culture. Journal of Biotechnology. 146(3):143-6.
2009
Buchholz DE, Hikita ST, Rowland TJ, Friedrich AM, Hinman CR, Johnson LV, Clegg DO.  2009.  Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells. Stem Cells. 27(10):2427-34.
Carr A-J, Vugler AA, Hikita ST, Lawrence JM, Gias C, Chen LLi, Buchholz DE, Ahmado A, Semo M'ayan, Smart MJK et al..  2009.  Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat. PLoS One. 4(12):e8152.
2008
Hikita ST, Kosik KS, Clegg DO, Bamdad C.  2008.  MUC1* mediates the growth of human pluripotent stem cells. PLoS One. 3(10):e3312.
2005
Putzke AP, Hikita ST, Clegg DO, Rothman JH.  2005.  Essential kinase-independent role of a Fer-like non-receptor tyrosine kinase in Caenorhabditis elegans morphogenesis. Development. 132(14):3185-95.
2004
Leu ST, Jacques SAL, Wingerd KL, Hikita ST, Tolhurst EC, Pring JL, Wiswell D, Kinney L, Goodman NL, Jackson DY et al..  2004.  Integrin alpha4beta1 function is required for cell survival in developing retina. Developmental Biology. 276(2):416-30.
2003
Clegg DO, Wingerd KL, Hikita ST, Tolhurst EC.  2003.  Integrins in the development, function and dysfunction of the nervous system. Frontiers in Bioscience: A Journal and Virtual Library. 8:d723-50.
2002
Leu ST, Batni S, Radeke MJ, Johnson LV, Anderson DH, Clegg DO.  2002.  Drusen are Cold Spots for Proteolysis: Expression of Matrix Metalloproteinases and Their Tissue Inhibitor Proteins in Age-related Macular Degeneration. Experimental Eye Research. 74(1):141-54.