Publications

Found 67 results
Author Title [ Type(Desc)] Year
Filters: Author is Clegg, Dennis O  [Clear All Filters]
Book Chapter
Clegg DO, Mullick LH, Wingerd KL, Lin H, Atienza JW, Bradshaw AD, Gervin DB, Cann GM.  2000.  Adhesive events in retinal development and function: the role of integrin receptors. Vertebrate Eye Development. :141–156.
Clegg DO, Buchholz D, Hikita S, Rowland T, Hu Q, Johnson LV.  2008.  Retinal pigment epithelial cells: development in vivo and derivation from human embryonic stem cells in vitro for treatment of age-related macular degeneration. Stem Cell Research and Therapeutics. :1–24.
Conference Paper
Pennington BOcean, Buchholz DE, Hinman C, Croze R, Coffey PJ, Clegg DO.  2013.  Rapid and efficient derivation of retinal pigment epithelium (RPE) from human pluripotent stem cells. FASEB Journal. 27
Gupta N, Campos LM, Hikita ST, Guino RG, Dimitriou MD, Given ELK, Clegg DO, Hawker CJ.  2008.  Thiol-ene hydrogels for cell culture and stem cell differentiation. Abstracts of Papers of the American Chemical Society. 235
Journal Article
Siegel KR, Clevenger TN, Clegg DO, Proctor DA, Proctor CS.  2017.  Adipose Stem Cells Incorporated in Fibrin Clot Modulate Expression of Growth Factors. Arthroscopy.
Wingerd KL, Goodman NL, Tresser JW, Smail MM, Leu ST, Rohan SJ, Pring JL, Jackson DY, Clegg DO.  2002.  Alpha4 integrins and vascular cell adhesion molecule-1 play a role in sympathetic innervation of the heart. The Journal of Neuroscience. 22(24):10772-80.
Hansma HG, Clegg DO, Kokkoli E, Oroudjev E, Tirrell M.  2002.  Analysis of matrix dynamics by atomic force microscopy. Methods in Cell Biology. 69:163–193.
Lin T-C, Seiler MJ, Zhu D, Falabella P, Hinton DR, Clegg DO, Humayun MS, Thomas BB.  2017.  Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models. Stem Cells Int. 2017:9428176.
Piunova V, Patel P, Lee C, Tsie M, Grubbs RH, Clegg DO.  2012.  Biodegradable polymer scaffolds for stem-cell based treatment of age-related macular degeneration.
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin C-M, Mitra D, Zhu D, Thomas BB et al..  2018.  A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration.. Science Translational Medicine. 10(435)
Leach LL, Buchholz DE, Nadar VP, Lowenstein SE, Clegg DO.  2015.  Canonical/β-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells. Investigative Ophthalmology & Visual Science. 56(2):1002-13.
Clevenger TN, Luna G, Boctor D, Fisher SK, Clegg DO.  2016.  Cell-mediated remodeling of biomimetic encapsulating hydrogels triggered by adipogenic differentiation of adipose stem cells. J Tissue Eng. 7:2041731416670482.
Forest DL, Johnson LV, Clegg DO.  2015.  Cellular models and therapies for age-related macular degeneration. Disease Models & Mechanisms. 8(5):421-7.
Leach LL, Clegg DO.  2015.  Concise Review: Making Stem Cells Retinal: Methods for Deriving Retinal Pigment Epithelium and Implications for Patients With Ocular Disease. Stem Cells. 33(8):2363-73.
Clegg DO, Rowland T.  2010.  Daniel E. Koshland Jr.. Proceedings of the American Philosophical Society. 154:477.
Pennington BO, Clegg DO, Melkoumian ZK, Hikita ST.  2015.  Defined culture of human embryonic stem cells and xeno-free derivation of retinal pigmented epithelial cells on a novel, synthetic substrate. Stem Cells Translational Medicine. 4(2):165-77.
Buchholz DE, Hikita ST, Rowland TJ, Friedrich AM, Hinman CR, Johnson LV, Clegg DO.  2009.  Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells. Stem Cells. 27(10):2427-34.
Rowland TJ, Blaschke AJ, Buchholz DE, Hikita ST, Johnson LV, Clegg DO.  2013.  Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins. Journal of Tissue Engineering and Regenerative Medicine. 7(8):642-53.
Croze RH, Clegg DO.  2014.  Differentiation of pluripotent stem cells into retinal pigmented epithelium. Developments in Ophthalmology. 53:81-96.
Leu ST, Batni S, Radeke MJ, Johnson LV, Anderson DH, Clegg DO.  2002.  Drusen are Cold Spots for Proteolysis: Expression of Matrix Metalloproteinases and Their Tissue Inhibitor Proteins in Age-related Macular Degeneration. Experimental Eye Research. 74(1):141-54.
Putzke AP, Hikita ST, Clegg DO, Rothman JH.  2005.  Essential kinase-independent role of a Fer-like non-receptor tyrosine kinase in Caenorhabditis elegans morphogenesis. Development. 132(14):3185-95.
Wingerd KL, Goodman NL, Leu ST, Clegg DO.  2004.  Expression and function of integrin alpha4beta1 and vascular cell adhesion molecule-1 (VCAM-1) during sympathetic innervation of the heart. Developmental Dynamics. 231(2):359-69.
Foltz LP, Howden SE, Thomson JA, Clegg DO.  2018.  Functional Assessment of Patient-Derived Retinal Pigment Epithelial Cells Edited by CRISPR/Cas9.. Int J Mol Sci. 19(12)
Gornalusse GG, Hirata RK, Funk SE, Riolobos L, Lopes VS, Manske G, Prunkard D, Colunga AG, Hanafi L-A, Clegg DO et al..  2017.  HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells. Nat Biotechnol.
Zhao T, Zhang Z-ning, Westenskow PD, Todorova D, Hu Z, Lin T, Rong Z, Kim J, He J, Wang M et al..  2015.  Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells. Cell Stem Cell. 17(3):353-9.

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