Publications

Found 125 results
Author Title [ Type(Asc)] Year
Journal Article
Croze RH, Thi WJ, Clegg DO.  2016.  ROCK Inhibition Promotes Attachment, Proliferation, and Wound Closure in Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium. Transl Vis Sci Technol. 5(6):7.
Croze RH, Buchholz DE, Radeke MJ, Thi WJ, Hu Q, Coffey PJ, Clegg DO.  2014.  ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium. Stem Cells Translational Medicine. 3(9):1066-78.
Sowden J, Beebe D, Powell C, Bird A, Cepko C, Clegg DO, Gamm DA, Goldman D, Hitchcock P, Hyde D et al..  2014.  Restoring Vision to the Blind: The Lasker/IRRF Initiative for Innovation in Vision Science.. Transl Vis Sci Technol. 3(7):1.
Hu Q, Chen R, Teesalu T, Ruoslahti E, Clegg DO.  2014.  Reprogramming human retinal pigmented epithelial cells to neurons using recombinant proteins. Stem Cells Translational Medicine. 3(12):1526-34.
Clegg DO, Large TH, Bodary SC, Reichardt LF.  1989.  Regulation of nerve growth factor mRNA levels in developing rat heart ventricle is not altered by sympathectomy. Developmental Biology. 134(1):30-7.
Clegg DO.  2016.  Regenerating Perfection. J Ocul Pharmacol Ther. 32(5):237.
Foltz LP, Clegg DO.  2017.  Rapid, Directed Differentiation of Retinal Pigment Epithelial Cells from Human Embryonic or Induced Pluripotent Stem Cells. J Vis Exp. (128)
Buchholz DE, Pennington BO, Croze RH, Hinman CR, Coffey PJ, Clegg DO.  2013.  Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium. Stem Cells Translational Medicine. 2(5):384-93.
Carr A-J, Vugler AA, Hikita ST, Lawrence JM, Gias C, Chen LLi, Buchholz DE, Ahmado A, Semo M'ayan, Smart MJK et al..  2009.  Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat. PLoS One. 4(12):e8152.
Pennington BO, Clegg DO.  2016.  Pluripotent Stem Cell-Based Therapies in Combination with Substrate for the Treatment of Age-Related Macular Degeneration. Journal of Ocular Pharmacology & Therapeutics.
Rowland TJ, Buchholz DE, Clegg DO.  2012.  Pluripotent human stem cells for the treatment of retinal disease. Journal of Cellular Physiology. 227(2):457-66.
Foltz LP, Clegg DO.  2018.  Patient-derived induced pluripotent stem cells for modelling genetic retinal dystrophies.. Progress in Retinal and Eye Research.
Hikita ST, Vistica BP, Jones HR, Keswani JR, Watson MM, Ericson VR, Ayoub GS, Gery I, Clegg DO.  2006.  Osteopontin is proinflammatory in experimental autoimmune uveitis. Investigative Ophthalmology & Visual Science. 47(10):4435-43.
Hikita S, Clegg DO.  2002.  Osteopontin is Expressed in Developing Mouse Retina and Supports Integrin-Dependent Neurite Outgrowth. Investigative Ophtalmology & Visual Science. 43:2698.
Hikita S, Clegg DO.  2004.  Osteopontin is Expressed in Developing Mouse Optic Tract and Supports Axon Extension of Retinal Ganglion Cells. Investigative Ophtalmology & Visual Science. 45:5371.
Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Chen S, Chan C, Palejwala N, Ingram A, Dang W et al..  2021.  One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration.. Transl Vis Sci Technol. 10(10):13.
Clegg DO.  2000.  Novel roles for integrins in the nervous system. Molecular Cell Biology Research Communications. 3:1–7.
Hu Y, Liu L, Lu B, Zhu D, Ribeiro R, Diniz B, Thomas PB, Ahuja AK, Hinton DR, Tai Y-C et al..  2012.  A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic Research. 48(4):186-91.
Large TH, Bodary SC, Clegg DO, Weskamp G, Otten U, Reichardt LF.  1986.  Nerve growth factor gene expression in the developing rat brain. Science. 234(4774):352-5.
Hikita ST, Kosik KS, Clegg DO, Bamdad C.  2008.  MUC1* mediates the growth of human pluripotent stem cells. PLoS One. 3(10):e3312.
Wang JY, Clegg DO, Koshland DE.  1981.  Molecular cloning and amplification of the adenylate cyclase gene. Proceedings of the National Academy of Sciences. 78(8):4684-8.
Neveu P, Kye MJeong, Qi S, Buchholz DE, Clegg DO, Sahin M, Park I-H, Kim K-S, Daley GQ, Kornblum HI et al..  2010.  MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states. Cell Stem Cell. 7(6):671-81.
Hu Q, Friedrich AM, Johnson LV, Clegg DO.  2010.  Memory in induced pluripotent stem cells: reprogrammed human retinal-pigmented epithelial cells show tendency for spontaneous redifferentiation. Stem Cells. 28(11):1981-91.
Huang X, Hu Q, Lai Y, Morales DP, Clegg DO, Reich NO.  2016.  Light-Patterned RNA Interference of 3D-Cultured Human Embryonic Stem Cells. Adv Mater. 28(48):10732-10737.
Huang X, Hu Q, Braun GB, Pallaoro A, Morales DP, Zasadzinski J, Clegg DO, Reich NO.  2015.  Light-activated RNA interference in human embryonic stem cells. Biomaterials. 63:70-9.

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