Publications

Found 125 results
Author Title Type [ Year(Asc)]
2016
Koss MJ, Falabella P, Stefanini FR, Pfister M, Thomas BB, Kashani AH, Brant R, Zhu D, Clegg DO, Hinton DR et al..  2016.  Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs. Graefes Arch Clin Exp Ophthalmol. 254(8):1553-65.
Thomas BB, Zhu D, Zhang L, Thomas PB, Hu Y, Nazari H, Stefanini F, Falabella P, Clegg DO, Hinton DR et al..  2016.  Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats. Invest Ophthalmol Vis Sci. 57(6):2877-87.
Clevenger TN, Hinman CR, Rubin RKAshley, Smither K, Burke DJ, Hawker CJ, Messina D, Van Epps D, Clegg DO.  2016.  Vitronectin-Based, Biomimetic Encapsulating Hydrogel Scaffolds Support Adipogenesis of Adipose Stem Cells. Tissue Engineering Part A. 22(7-8):597-609.
2015
Leach LL, Buchholz DE, Nadar VP, Lowenstein SE, Clegg DO.  2015.  Canonical/β-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells. Investigative Ophthalmology & Visual Science. 56(2):1002-13.
Forest DL, Johnson LV, Clegg DO.  2015.  Cellular models and therapies for age-related macular degeneration. Disease Models & Mechanisms. 8(5):421-7.
Leach LL, Clegg DO.  2015.  Concise Review: Making Stem Cells Retinal: Methods for Deriving Retinal Pigment Epithelium and Implications for Patients With Ocular Disease. Stem Cells. 33(8):2363-73.
Pennington BO, Clegg DO, Melkoumian ZK, Hikita ST.  2015.  Defined culture of human embryonic stem cells and xeno-free derivation of retinal pigmented epithelial cells on a novel, synthetic substrate. Stem Cells Translational Medicine. 4(2):165-77.
Zhao T, Zhang Z-ning, Westenskow PD, Todorova D, Hu Z, Lin T, Rong Z, Kim J, He J, Wang M et al..  2015.  Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells. Cell Stem Cell. 17(3):353-9.
Huang X, Hu Q, Braun GB, Pallaoro A, Morales DP, Zasadzinski J, Clegg DO, Reich NO.  2015.  Light-activated RNA interference in human embryonic stem cells. Biomaterials. 63:70-9.
Nazari H, Zhang L, Zhu D, Chader GJ, Falabella P, Stefanini F, Rowland T, Clegg DO, Kashani AH, Hinton DR et al..  2015.  Stem cell based therapies for age-related macular degeneration: The promises and the challenges. Progress in Retinal & Eye Research. 48:1-39.
2014
Croze RH, Clegg DO.  2014.  Differentiation of pluripotent stem cells into retinal pigmented epithelium. Developments in Ophthalmology. 53:81-96.
Pennington BO, Sears D, Clegg DO.  2014.  Interactive Hangman teaches amino acid structures and abbreviations. Biochemistry & Moleluclar Biology Education. 42(6):495-500.
Hu Q, Chen R, Teesalu T, Ruoslahti E, Clegg DO.  2014.  Reprogramming human retinal pigmented epithelial cells to neurons using recombinant proteins. Stem Cells Translational Medicine. 3(12):1526-34.
Sowden J, Beebe D, Powell C, Bird A, Cepko C, Clegg DO, Gamm DA, Goldman D, Hitchcock P, Hyde D et al..  2014.  Restoring Vision to the Blind: The Lasker/IRRF Initiative for Innovation in Vision Science.. Transl Vis Sci Technol. 3(7):1.
Croze RH, Buchholz DE, Radeke MJ, Thi WJ, Hu Q, Coffey PJ, Clegg DO.  2014.  ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium. Stem Cells Translational Medicine. 3(9):1066-78.
2013
Clegg DO, Hikita ST, Hu Q, Buchholz DE, Rowland TJ, Conti L, Pennington B, Croze R, Leach L, Tsie M et al..  2013.  Derivation of retinal pigmented epithelial cells from pluripotent stem cells. The Stem Cell Handbook.
Rowland TJ, Blaschke AJ, Buchholz DE, Hikita ST, Johnson LV, Clegg DO.  2013.  Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins. Journal of Tissue Engineering and Regenerative Medicine. 7(8):642-53.
Hikita S, Clegg D, Johnson L, Miller L, Tsie M, Presbrey C, Conti L, Maloney M, Hinton D, Hu Q et al..  2013.  Methods of Culturing Retinal Pigmented Epithelium Cells, Including Xeno-Free Production, RPE Enrichment, and Cryopreservation.
Pennington BOcean, Buchholz DE, Hinman C, Croze R, Coffey PJ, Clegg DO.  2013.  Rapid and efficient derivation of retinal pigment epithelium (RPE) from human pluripotent stem cells. FASEB Journal. 27
Buchholz DE, Pennington BO, Croze RH, Hinman CR, Coffey PJ, Clegg DO.  2013.  Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium. Stem Cells Translational Medicine. 2(5):384-93.
2012
Piunova V, Patel P, Lee C, Tsie M, Grubbs RH, Clegg DO.  2012.  Biodegradable polymer scaffolds for stem-cell based treatment of age-related macular degeneration.
Hu Y, Liu L, Lu B, Zhu D, Ribeiro R, Diniz B, Thomas PB, Ahuja AK, Hinton DR, Tai Y-C et al..  2012.  A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic Research. 48(4):186-91.
Rowland TJ, Buchholz DE, Clegg DO.  2012.  Pluripotent human stem cells for the treatment of retinal disease. Journal of Cellular Physiology. 227(2):457-66.
Gupta N, Lin BF, Campos LM, Dimitriou MD, Hikita ST, Treat ND, Tirrell MV, Clegg DO, Kramer EJ, Hawker CJ.  2012.  A versatile approach to high-throughput microarrays using thiol-ene chemistry. Nature Chemistry. 4:424–424.
2011
Ahuja A, Clegg D, Grubbs R, Hinton D, Humayun M, Tai YC.  2011.  Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same.

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