| Title | NEGotiating Cell Identity through Regulated Cytoplasmic Polyadenylation. |
| Publication Type | Journal Article |
| Year of Publication | 2015 |
| Authors | Joshi PM, Rothman JH |
| Journal | Dev Cell |
| Volume | 34 |
| Issue | 1 |
| Pagination | 1-2 |
| Date Published | 2015 Jul 6 |
| ISSN | 1878-1551 |
| Keywords | Animals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Carrier Proteins, Cytoplasm, Nuclear Proteins, Polyadenylation, RNA, Helminth, RNA, Messenger |
| Abstract | In this issue of Developmental Cell, Elewa et al. (2015) show that combinatorial action of RNA binding proteins modulates poly(A) tail length of maternal mRNAs, leading to asymmetric expression of a cell fate determinant in early C. elegans embryos. Genome-wide profiling suggests this mechanism may be widely used to establish cell identities. |
| DOI | 10.1016/j.devcel.2015.06.022 |
| Alternate Journal | Dev. Cell |
| PubMed ID | 26151901 |