Cell fusion: EFF is enough.

TitleCell fusion: EFF is enough.
Publication TypeJournal Article
Year of Publication2005
AuthorsKontani K, Rothman JH
JournalCurr Biol
Volume15
Issue7
PaginationR252-4
Date Published2005 Apr 12
ISSN0960-9822
KeywordsAnimals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Cell Fusion, Epithelial Cells, Membrane Glycoproteins, Models, Biological, Protein Binding, Protein Structure, Tertiary
Abstract

Developmentally programmed cell-cell fusion in Caenorhabditis elegans requires the EFF-1 protein, which is sufficient to cause normally non-fusing cells to fuse. EFF-1 localizes to fusion-fated membranes, implicating it as a direct fusogen.

DOI10.1016/j.cub.2005.03.020
Alternate JournalCurr. Biol.
PubMed ID15823525