Title | Cell fusion: EFF is enough. |
Publication Type | Journal Article |
Year of Publication | 2005 |
Authors | Kontani K, Rothman JH |
Journal | Curr Biol |
Volume | 15 |
Issue | 7 |
Pagination | R252-4 |
Date Published | 2005 Apr 12 |
ISSN | 0960-9822 |
Keywords | Animals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Cell Fusion, Epithelial Cells, Membrane Glycoproteins, Models, Biological, Protein Binding, Protein Structure, Tertiary |
Abstract | Developmentally programmed cell-cell fusion in Caenorhabditis elegans requires the EFF-1 protein, which is sufficient to cause normally non-fusing cells to fuse. EFF-1 localizes to fusion-fated membranes, implicating it as a direct fusogen. |
DOI | 10.1016/j.cub.2005.03.020 |
Alternate Journal | Curr. Biol. |
PubMed ID | 15823525 |