Title | Gastrulation: PARtaking of the bottle. |
Publication Type | Journal Article |
Year of Publication | 2003 |
Authors | Putzke AP, Rothman JH |
Journal | Curr Biol |
Volume | 13 |
Issue | 6 |
Pagination | R223-5 |
Date Published | 2003 Mar 18 |
ISSN | 0960-9822 |
Keywords | Actin Cytoskeleton, Animals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Cell Polarity, Gastrula, Microtubules, Models, Biological, Protein-Serine-Threonine Kinases |
Abstract | Gastrulation in C. elegans embryos involves ingression of individual cells, but is driven by apical constriction of the kind that promotes migration of epithelial cell sheets. Recent work shows that PAR proteins, known for their role in polarization and unequal cell division, are also associated with the polarization that establishes this apical constriction. |
Alternate Journal | Curr. Biol. |
PubMed ID | 12646146 |