Cell fusion: an EFFicient sculptor.

TitleCell fusion: an EFFicient sculptor.
Publication TypeJournal Article
Year of Publication2002
AuthorsWitze E, Rothman JH
JournalCurr Biol
Volume12
Issue13
PaginationR467-9
Date Published2002 Jul 9
ISSN0960-9822
KeywordsAnimals, Caenorhabditis elegans, Caenorhabditis elegans Proteins, Membrane Fusion, Membrane Glycoproteins
Abstract

Mutations in the eff-1 gene of Caenorhabditis elegans, which prevent all cell-cell fusions in the nematode's epidermis, have revealed developmental roles for cell fusion. An extracellular fusogen-like domain in EFF-1 suggests it might direct the fusion of lipid bilayers.

Alternate JournalCurr. Biol.
PubMed ID12121640