Programmed Cell Death, Cell Proliferation, and Cancer Biology

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Researchers

Joel Rothman

Regulation of development and differentiation; regulation of programmed cell death and cell division; mechanisms of tumorigenesis

My research investigates the apoptotic and non-apoptotic roles of programmed cell death (PCD) regulators during cellular growth, proliferation, reprogramming and mitochondrial purifying selection in the C. elegans germline. I am also investigating the role of mitochondria and hormesis in aging and longevity as well as the regulation of adult germline stem cell (GSC) homeostasis by microRNAs.

Cricket Wood

I participate in and support several different research projects within the lab while managing the day to day running of the lab.

Juwel Chandra Baray

My research is centered on understanding transdifferentiation, transorganogenesis, and the intriguing fields of aging and longevity in the nematode C. elegans. Furthermore, my objective is to bridge the gap between human biology and model organisms by applying these insights to the context of human cells.

Irene Chaey

I am working with Dr. Joshi to uncover the molecular pathway by which cell death regulators recycle defective mitochondrial DNA in the C. elegans germline.