Programmed Cell Death, Cell Proliferation, and Cancer Biology
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Researchers
Joel Rothman
Regulation of development and differentiation; regulation of programmed cell death and cell division; mechanisms of tumorigenesis
Pradeep Joshi
My research investigates the coordination between cell proliferation and differentiation using C. elegans germline stem cells (GSCs) as a paradigm. Research areas: Role of microRNAs in maintaining adult GSC homeostasis and buffering noise in the underlying gene regulatory network; Non-apoptotic roles of programmed cell death regulators during cellular growth, proliferation, and reprogramming.
Cricket Wood
I participate in and support several different research projects within the lab while managing the day to day running of the lab.
Juwel Chandra Baray
My research is centered on understanding transdifferentiation, transorganogenesis, and the intriguing fields of aging and longevity in the nematode C. elegans. Furthermore, my objective is to bridge the gap between human biology and model organisms by applying these insights to the context of human cells.
Abhayjit S. Saini
My current research focuses on establishing the role of caspases in mitochondrial purifying selection. I primarily focus on the Programmed Cell Death pathway and the aging pathway and use C elegans as a model organism to understand the mechanism of mtDNA purifying selection in the germline.
Azure Paxton
We are currently working to determine the genes involved in cell death in the germline by knocking out genes and performing a cell death assay using the acridine orange staining technique