Stem Cell Biology, Developmental Plasticity, and Cellular Reprogramming

Researchers

Pradeep Joshi

My research investigates the coordination between cell proliferation and differentiation using C. elegans germline stem cells (GSCs) as a paradigm. Research areas: Role of microRNAs in maintaining adult GSC homeostasis and buffering noise in the underlying gene regulatory network; Non-apoptotic roles of programmed cell death regulators during cellular growth, proliferation, and reprogramming.

Cricket Wood

I participate in and support several different research projects within the lab while managing the day to day running of the lab.

Juwel Chandra Baray

My research is centered on understanding transdifferentiation, transorganogenesis, and the intriguing fields of aging and longevity in the nematode C. elegans. Furthermore, my objective is to bridge the gap between human biology and model organisms by applying these insights to the context of human cells.

Anna Jellema-Butler

I am interested in understanding the mechanisms controlling healthspan and lifespan, including the role of genetic and epigenetic factors, natural and artificial rejuvenation events, and dietary and behavioral interventions. I work with the premier aging model of C. elegans and focus on leveraging large-scale biological data through the use of statistics and bioinformatics. 

Sierra Klier

My research focuses on transcriptomic analysis of the processes we study in the lab. In particular, I am interested in changes in gene regulation during recovery from extreme stress in tardigrades, as well as the transcriptional changes in C. Elegans as they undergo transdifferentiation.

Perrine Changkuon

I work with Juwel on projects relating to aging and longevity in C. elegans and understanding the mechanisms that increase their lifespan.

Carina Chen

I am working with Juwel Chandra Baray on projects relating to trans-differentiation and longevity in C. elegans. I am interested in the protein models of possible direct reprogramming genes that cause trans-differentiation and in creating a predictive model of the areas of interest for each gene.

Pihu Jain

I work with Sierra Klier in research relating to C. elegans transdifferentiation.

Research Collaborators

Department of Engineering
UCSB