Publications

Found 21 results
Author Title [ Type(Desc)] Year
Filters: Keyword is Mutation and Author is Joel H Rothman  [Clear All Filters]
Journal Article
Rothman JH, Yamashiro CT, Raymond CK, Kane PM, Stevens TH.  1989.  Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins.. J Cell Biol. 109(1):93-100.
Sugimoto A, Friesen PD, Rothman JH.  1994.  Baculovirus p35 prevents developmentally programmed cell death and rescues a ced-9 mutant in the nematode Caenorhabditis elegans.. EMBO J. 13(9):2023-8.
Derry WB, Putzke AP, Rothman JH.  2001.  Caenorhabditis elegans p53: role in apoptosis, meiosis, and stress resistance.. Science. 294(5542):591-5.
Koh K, Peyrot SM, Wood CG, Wagmaister JA, Maduro MF, Eisenmann DM, Rothman JH.  2002.  Cell fates and fusion in the C. elegans vulval primordium are regulated by the EGL-18 and ELT-6 GATA factors -- apparent direct targets of the LIN-39 Hox protein.. Development. 129(22):5171-80.
Rothman JH, Howald I, Stevens TH.  1989.  Characterization of genes required for protein sorting and vacuolar function in the yeast Saccharomyces cerevisiae.. EMBO J. 8(7):2057-65.
Moskowitz IP, Gendreau SB, Rothman JH.  1994.  Combinatorial specification of blastomere identity by glp-1-dependent cellular interactions in the nematode Caenorhabditis elegans.. Development. 120(11):3325-38.
Maduro MF, Lin R, Rothman JH.  2002.  Dynamics of a developmental switch: recursive intracellular and intranuclear redistribution of Caenorhabditis elegans POP-1 parallels Wnt-inhibited transcriptional repression.. Dev Biol. 248(1):128-42.
Fukuyama M, Gendreau SB, W Derry B, Rothman JH.  2003.  Essential embryonic roles of the CKI-1 cyclin-dependent kinase inhibitor in cell-cycle exit and morphogenesis in C elegans.. Dev Biol. 260(1):273-86.
Maduro MF, Broitman-Maduro G, Mengarelli I, Rothman JH.  2007.  Maternal deployment of the embryonic SKN-1-->MED-1,2 cell specification pathway in C. elegans.. Dev Biol. 301(2):590-601.
Rothman JH, Hunter CP, Valls LA, Stevens TH.  1986.  Overproduction-induced mislocalization of a yeast vacuolar protein allows isolation of its structural gene.. Proc Natl Acad Sci U S A. 83(10):3248-52.
Rothman JH, Stevens TH.  1986.  Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway.. Cell. 47(6):1041-51.
Valls LA, Hunter CP, Rothman JH, Stevens TH.  1987.  Protein sorting in yeast: the localization determinant of yeast vacuolar carboxypeptidase Y resides in the propeptide.. Cell. 48(5):887-97.
Kane PM, Yamashiro CT, Rothman JH, Stevens TH.  1989.  Protein sorting in yeast: the role of the vacuolar proton-translocating ATPase.. J Cell Sci Suppl. 11:161-78.
Rothman JH, Yamashiro CT, Kane PM, Stevens TH.  1989.  Protein targeting to the yeast vacuole.. Trends Biochem Sci. 14(8):347-50.
Rothman JH, Raymond CK, Gilbert T, O'Hara PJ, Stevens TH.  1990.  A putative GTP binding protein homologous to interferon-inducible Mx proteins performs an essential function in yeast protein sorting.. Cell. 61(6):1063-74.
Kontani K, Moskowitz IPG, Rothman JH.  2005.  Repression of cell-cell fusion by components of the C. elegans vacuolar ATPase complex.. Dev Cell. 8(5):787-94.
Maduro MF, Meneghini MD, Bowerman B, Broitman-Maduro G, Rothman JH.  2001.  Restriction of mesendoderm to a single blastomere by the combined action of SKN-1 and a GSK-3beta homolog is mediated by MED-1 and -2 in C. elegans.. Mol Cell. 7(3):475-85.
Ferguson KC, Heid PJ, Rothman JH.  1996.  The SL1 trans-spliced leader RNA performs an essential embryonic function in Caenorhabditis elegans that can also be supplied by SL2 RNA.. Genes Dev. 10(12):1543-56.
Kodama Y, Rothman JH, Sugimoto A, Yamamoto M.  2002.  The stem-loop binding protein CDL-1 is required for chromosome condensation, progression of cell death and morphogenesis in Caenorhabditis elegans.. Development. 129(1):187-96.
Bloss TA, Witze ES, Rothman JH.  2003.  Suppression of CED-3-independent apoptosis by mitochondrial betaNAC in Caenorhabditis elegans.. Nature. 424(6952):1066-71.
Heid PJ, Raich WB, Smith R, Mohler WA, Simokat K, Gendreau SB, Rothman JH, Hardin J.  2001.  The zinc finger protein DIE-1 is required for late events during epithelial cell rearrangement in C. elegans.. Dev Biol. 236(1):165-80.