News

June 15, 2016

Dr. Weimbs has been awarded a Faculty Research Grant by the UCSB Academic Senate for the funding period 07/01/16-6/31/17. The title of the winning proposal was "Development of a tissue‐targeted therapeutic antibody for treatment of polycystic kidney disease." This research project is based on a patent-pending technology invented in the Weimbs lab that may enable the "repurposing" of existing antibody therapeutics for treatment of PKD.

June 09, 2016

Brandon E. Rose is the recipient of the Jeremy D. Friedman Memorial Award, which recognizes outstanding leadership, superior scholarship and contributions to undergraduate life on campus. Mr. Rose is a Cell & Developmental Biology major in MCDB and conducts biomedical research in the lab of MCDB professor Thomas Weimbs. 

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June 07, 2016

Congratulations to Sammi Kruger, undergraduate student in the Weimbs lab, who was awarded First Place in the category Science, Math & Engineering for her research poster presented at the 2016 Undergraduate Research Colloquium. Her poster was titled "Folate-Conjugated Rapamycin Improves Polycystic Kidney Disease in a PKD1 Inactivated Model."

March 02, 2016

Our latest paper titled "A mild reduction of food intake slows disease progression in an orthologous mouse model of polycystic kidney disease" was chosen for APSselect, a collection of the very best original research papers published by the American Physiological Society.

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February 17, 2016

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January 28, 2016

Members of the Thomas Weimbs Lab demonstrate that reducing food intake in mice diminishes the growth of their polycystic kidneys. Read more:

UCSB News Release

The American Physiological Society Press Release

 

December 07, 2015

Congratulations to Jesse Benza, Sammatha Kruger, Ali Michelotti and Kian Rahbari for each being awarded Undergraduate Research and Creative Activities (URCA) Research Grants to support their research projects in the Weimbs lab. Each award is in the amount of $750.

June 25, 2015

Delivering Drugs to the Right Place

MCDB professor Thomas Weimbs and his team have developed a targeted drug delivery method that could potentially slow the progression of polycystic kidney disease. Weimbs and his team have found a method that enables a class of antibodies, immunoglobulin-A (IgA), to penetrate the cyst walls in PKD kidneys. The strategy opens up the possibility of repurposing a large number of existing drugs for PKD therapy. The researchers’ results appear in the Journal of Biological Chemistry.

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June 19, 2015

The latest paper from the Weimbs lab, titled "Exploitation of the Polymeric Immunoglobulin Receptor for Antibody Targeting to Renal Cyst Lumens in Polycystic Kidney Disease", just came out in print in the June 19 issue of the Journal of Biological Chemistry. Click below for the PDF file.

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December 08, 2014

Congratulations to Jesse Benza, Elyse Dewey, Claudia Jette, Maddison Kane, Solomiya Kryshtafovych, Katherine Lee, Madelyn Mar, Sirpi Nackeeran, and Pasha Rahbari for each being awarded Undergraduate Research and Creative Activities (URCA) Research Grants to support their research projects in the Weimbs lab. Each award is in the amount of $750.

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