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New paper published in Cell Reports Medicine

September 16, 2025

Development of a cyst-targeted therapy for polycystic kidney disease using an antagonistic dimeric IgA monoclonal antibody against cMET

Margaret F Schimmel 1, Bryan C Bourgeois 1, Alison K Spindt 1, Sage A Patel 1, Tiffany Chin 1, Gavin E Cornick 1, Yuqi Liu 1, Thomas Weimbs 2

DOI: 10.1016/j.xcrm.2025.102335

 

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The Hormone That Could Reverse Kidney Disease | Thomas Weimbs on Podcast

September 04, 2025

Degrees of Health Podcast

'High-protein diets hurt your kidneys!'. 'Once kidney disease starts, it only gets worse'. Heard something similar? It's just not the whole picture and also showing to be quite far from the truth.

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https://youtu.be/LK7ot8dnGo4

Collaborative paper published about ketogenic metabolic therapy for long-COVID recovery

August 25, 2025

Colgan, D. D.; Stadler, D. D.; Hope, A. A.; Zwickey, H.; Davenport, T. E.; Weimbs, T. Clinically Meaningful Improvements in Long COVID Symptoms Following Ketogenic Metabolic Therapy Combined with Lifestyle Interventions - A Clinical Case Report and Review of the Literature. CRCM 2025, 14 (08), 391–410.

Abstract:

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Link to paperhttps://doi.org/10.4236/crcm.2025.148052

Podcast by Dr. Ovadia featuring our research on polycystic kidney disease

July 08, 2025

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Melina Messing receives 2025 Jared J. Grantham Research Fellowship Award

July 01, 2025

Congratulations to Melina Messing, PhD for receiving the 2025 Jared J. Grantham Research Fellowship Award to support her research in the Weimbs laboratory. Melina will study "Immune Mechanisms Underlying Efficacy of Ketogenic Metabolic Therapy in Polycystic Kidney Disease".

 

 

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Collaborative paper with Virta Health published

June 06, 2025

Athinarayanan, S. J.; Roberts, C. G. P.; Phinney, S. D.; Weimbs, T.; Friedman, A. N.; Volek, J. S. Effects of a Continuous Remote Care Intervention Including Nutritional Ketosis on Kidney Function and Inflammation in Adults with Type 2 Diabetes: A Post-Hoc Latent Class Trajectory Analysis. Front. Nutr. 2025, 12. https://doi.org/10.3389/fnut.2025.1609737.

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https://doi.org/10.3389/fnut.2025.1609737

Emily Ngo chosen as UC LEADS Scholar

May 10, 2025

Congratulations to Weimbs Lab undergraduate researcher Emily Ngo who has been accepted to the University of California Leadership Excellence through Advanced Degrees (UC LEADS) program for the 2025-27 Scholar Cohort

New review article published explaining how polycystic kidney disease progression is not just driven by genetics but by nutrition and lifestyle triggers

October 31, 2024

Messing, Melina, Jacob A. Torres, Nickolas Holznecht, and Thomas Weimbs. “Trigger Warning: How Modern Diet, Lifestyle, and Environment Pull the Trigger on Autosomal Dominant Polycystic Kidney Disease Progression.” Nutrients 16, no. 19 (January 2024): 3281.

https://doi.org/10.3390/nu16193281

 

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New paper published in iScience

September 27, 2024

Congratulations to all authors!

Torres, J. A.; Holznecht, N.; Asplund, D. A.; Kroes, B. C.; Amarlkhagva, T.; Haeffner, M. M.; Sharpe, E. H.; Koestner, S.; Strubl, S.; Schimmel, M. F.; Kruger, S.; Agrawal, S.; Aceves, B. A.; Thangaraju, M.; Weimbs, T. β-Hydroxybutyrate Recapitulates the Beneficial Effects of Ketogenic Metabolic Therapy in Polycystic Kidney Disease. iScience 2024, 27 (9). https://doi.org/10.1016/j.isci.2024.110773.

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New review article published titled "The case for a ketogenic diet in the management of kidney disease"

April 29, 2024

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