Congratulations to all authors!

Messing M, Muensterman E, Marcon S, Weimbs T. Halting cyst progression in ADPKD using long-term ketogenic metabolic therapy and supplementation with exogenous ketones and alkaline citrate—a case series. Frontiers in Nutrition. 2026 ;13:1843178.

Abstract: 

Abstract

Background: Autosomal-dominant polycystic kidney disease (ADPKD) is a common hereditary form of chronic kidney disease with limited pharmacological treatment options. Emerging evidence suggests that metabolic interventions, including ketogenic dietary strategies and reducing lithogenic risk, may positively influence disease progression.

News release about our study on developing a new class of monoclonal antibody drugs for polycystic kidney disease therapy. These dimeric-IgA class antibodies have the ability to target to cyst lumens in PKD.

A ‘magic bullet’ for polycystic kidney disease in the making

Polycystic kidney disease (PKD) is a debilitating hereditary condition in which fluid-filled sacs form and proliferate in the kidneys. Over time, the painful, growing cysts rob the organs of their function, often leading to dialysis in advanced cases There is currently no cure.

Degrees of Health Podcast

'High-protein diets hurt your kidneys!'. 'Once kidney disease starts, it only gets worse'. Heard something similar? It's just not the whole picture and also showing to be quite far from the truth.