Members

Principal Investigator

Carolina Arias

Principal Investigator

Project Scientists

Dr. Braig-Karzig is the Lab Manager for both Dr. Arias and Dr. Acosta-Alvear's labs

Veronica is interested in delineating host transcriptional changes following KSHV infection of primary endothelial cells through computational analysis of RNA-Seq data

Graduate Students

Oran is a M.S. student investigating the piracy and manipulation of the ZIKA virus in relation to translation initiation, particularly with regard to differential expression of the components of eIF4F

Guilermo is a Ph.D. student who is exploring the dynamics of the UPR in cells infected with KSHV and is specifically interested in identifying viral factors affecting this cellular response

Duncan is a Ph.D. student interested in the effects of Zika virus on eye development and health, primarily pertaining to the activation and inhibition of cellular stress responses by Zika

Undergraduate Students

Catya is investigating how KSHV adapts to acute and chronic UPR stress

Roy is studying the function of KSHV's novel viral small open reading frame PAN 1.1

Michelle will be optimizing a Cas9 based system for virus mutagenesis in order to investigate the function of novel KSHV smORFs

Shannon is exploring KSHV's viral control of translation

Mary is optimizing methods for studying viral gene functions, particularly with regard to KSHV, in latently infected mammalian cells through use of CRISPRi

Colleen has been working on optimizing a CRISPR-Cas9 based method for the mutagenesis of KSHV's viral genome and is also investigating the effects of Zika virus exposure on the eye during development

GIl is exploring the structure of KSHV chromatin during the lytic cycle and how Zika Virus interacts with the UPR

Technical Staff

As an undergraduate lab technician, Justin helps keep the Arias Lab's supplies and resources prepped to facilitate research

Alumni

Ezra worked on characterizing the biochemical significance of the 3' UTR in the Zika Virus genome. 

Ameera is an Arias Lab alumna who previously worked on developing a CRISPRi system for silencing KSHV genes in different host cell lines. She is now a researcher at NIH in the Medical Genetics and Ophthalmic Genomics Unit